Determining epigenetic memory in kidney proximal tubule cell derived induced pluripotent stem cells using a quadruple transgenic reprogrammable mouse

The majority of nucleated somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs). The process of reprogramming involves epigenetic remodelling to turn on pluripotency-associated genes and turn off lineage-specific genes. Some evidence shows that iPSCs retain epigenetic marks of...

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Detalles Bibliográficos
Autores principales: Khelifi, Gabriel, Chow, Theresa, Whiteley, Jennifer, Fort, Victoire, Humphreys, Benjamin D., Hussein, Samer M.I., Rogers, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700797/
https://www.ncbi.nlm.nih.gov/pubmed/36434072
http://dx.doi.org/10.1038/s41598-022-24581-z

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