GPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophages

G-protein-signaling modulator 1 (GPSM1) exhibits strong genetic association with Type 2 diabetes (T2D) and Body Mass Index in population studies. However, how GPSM1 carries out such control and in which types of cells are poorly understood. Here, we demonstrate that myeloid GPSM1 promotes metabolic...

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Detalles Bibliográficos
Autores principales: Yan, Jing, Zhang, Yuemei, Yu, Hairong, Zong, Yicen, Wang, Daixi, Zheng, Jiangfei, Jin, Li, Yu, Xiangtian, Liu, Caizhi, Zhang, Yi, Jiang, Feng, Zhang, Rong, Fang, Xiangnan, Xu, Ting, Li, Mingyu, Di, Jianzhong, Lu, Yan, Ma, Xinran, Zhang, Jian, Jia, Weiping, Hu, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700814/
https://www.ncbi.nlm.nih.gov/pubmed/36434066
http://dx.doi.org/10.1038/s41467-022-34998-9

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