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Insights into protein post-translational modification landscapes of individual human cells by trapped ion mobility time-of-flight mass spectrometry

Single cell proteomics is a powerful tool with potential for markedly enhancing understanding of cellular processes. Here we report the development and application of multiplexed single cell proteomics using trapped ion mobility time-of-flight mass spectrometry. When employing a carrier channel to i...

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Detalles Bibliográficos
Autores principales: Orsburn, Benjamin C., Yuan, Yuting, Bumpus, Namandjé N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700839/
https://www.ncbi.nlm.nih.gov/pubmed/36433961
http://dx.doi.org/10.1038/s41467-022-34919-w