Cargando…
Examining the source of increased bipolar disorder and major depressive disorder common risk variation burden in multiplex schizophrenia families
Psychotic and affective disorders often aggregate in the relatives of probands with schizophrenia, and genetic studies show substantial genetic correlation among schizophrenia, bipolar disorder, and major depressive disorder. In this study, we examined the polygenic risk burden of bipolar disorder a...
Autores principales: | Ahangari, Mohammad, Kirkpatrick, Robert, Nguyen, Tan-Hoang, Gillespie, Nathan, Kendler, Kenneth S., Bacanu, Silviu-Alin, Webb, Bradley T., Verrelli, Brian C., Riley, Brien P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700852/ https://www.ncbi.nlm.nih.gov/pubmed/36434002 http://dx.doi.org/10.1038/s41537-022-00317-w |
Ejemplares similares
-
Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families
por: Ahangari, Mohammad, et al.
Publicado: (2022) -
Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia
por: Ahangari, Mohammad, et al.
Publicado: (2023) -
TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders
por: Chatzinakos, Chris, et al.
Publicado: (2020) -
Transcriptome Sequencing and Genome-wide Association Analyses Reveal Lysosomal Function and Actin Cytoskeleton Remodeling in Schizophrenia and Bipolar Disorder
por: Zhao, Zhongming, et al.
Publicado: (2014) -
A simple yet accurate correction for winner's curse can predict signals discovered in much larger genome scans
por: Bigdeli, T. Bernard, et al.
Publicado: (2016)