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Transcriptomic analysis of a 3D blood–brain barrier model exposed to disturbed fluid flow
Cerebral aneurysms are more likely to form at bifurcations in the vasculature, where disturbed fluid is prevalent due to flow separation at sufficiently high Reynolds numbers. While previous studies have demonstrated that altered shear stress exerted by disturbed flow disrupts endothelial tight junc...
Autores principales: | Bouhrira, Nesrine, DeOre, Brandon J., Tran, Kiet A., Galie, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700938/ https://www.ncbi.nlm.nih.gov/pubmed/36434717 http://dx.doi.org/10.1186/s12987-022-00389-x |
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