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Identification of potential immunomodulators from Pulsatilla decoction that act on therapeutic targets for ulcerative colitis based on pharmacological activity, absorbed ingredients, and in-silico molecular docking

BACKGROUND: Pulsatilla decoction (Bai-Tou-Weng-Tang, BTWT) is a classic formula prescription of a traditional Chinese medicine that is used to treat ulcerative colitis (UC). However, its active components and underlying mechanism of action remain unclear. In the present study, we aimed to identify p...

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Detalles Bibliográficos
Autores principales: Deng, Li-rong, Han, Qian, Zou, Min, Chen, Fang-jun, Huang, Chang-yin, Zhong, Yi-ming, Wu, Qian-yan, Tomlinson, Brian, Li, Yan-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701001/
https://www.ncbi.nlm.nih.gov/pubmed/36434688
http://dx.doi.org/10.1186/s13020-022-00684-7