Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus

Crimean-Congo Hemorrhagic Fever Virus (CCHFV) causes a life-threatening disease with up to a 40% mortality rate. With no approved medical countermeasures, CCHFV is considered a public health priority agent. The non-neutralizing mouse monoclonal antibody (mAb) 13G8 targets CCHFV glycoprotein GP38 and...

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Detalles Bibliográficos
Autores principales: Durie, Ian A., Tehrani, Zahra R., Karaaslan, Elif, Sorvillo, Teresa E., McGuire, Jack, Golden, Joseph W., Welch, Stephen R., Kainulainen, Markus H., Harmon, Jessica R., Mousa, Jarrod J., Gonzalez, David, Enos, Suzanne, Koksal, Iftihar, Yilmaz, Gurdal, Karakoc, Hanife Nur, Hamidi, Sanaz, Albay, Cansu, Spengler, Jessica R., Spiropoulou, Christina F., Garrison, Aura R., Sajadi, Mohammad M., Bergeron, Éric, Pegan, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701186/
https://www.ncbi.nlm.nih.gov/pubmed/36435827
http://dx.doi.org/10.1038/s41467-022-34923-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701186/
https://www.ncbi.nlm.nih.gov/pubmed/36435827
http://dx.doi.org/10.1038/s41467-022-34923-0

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