Greater genetic diversity is needed in human pluripotent stem cell models

While there are a growing number of human pluripotent stem cell repositories, genetic diversity remains limited in most collections and studies. Here, we discuss the importance of incorporating diverse ancestries in these models to improve equity and accelerate biological discovery.

Detalles Bibliográficos
Autores principales: Ghosh, Sulagna, Nehme, Ralda, Barrett, Lindy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701202/
https://www.ncbi.nlm.nih.gov/pubmed/36435871
http://dx.doi.org/10.1038/s41467-022-34940-z
Descripción
Sumario:While there are a growing number of human pluripotent stem cell repositories, genetic diversity remains limited in most collections and studies. Here, we discuss the importance of incorporating diverse ancestries in these models to improve equity and accelerate biological discovery.

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