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A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles

Vaccines against infectious diseases should elicit potent and long-lasting immunity, ideally even in those with age-related decline in immune response. Here we report a rational polysaccharide vaccine platform using probiotic Escherichia coli-derived membrane vesicles (MVs). First, we constructed a...

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Detalles Bibliográficos
Autores principales:	Nakao, Ryoma, Kobayashi, Hirotaka, Iwabuchi, Yusuke, Kawahara, Kazuyoshi, Hirayama, Satoru, Ramstedt, Madeleine, Sasaki, Yuki, Kataoka, Michiyo, Akeda, Yukihiro, Ohnishi, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701205/ https://www.ncbi.nlm.nih.gov/pubmed/36435869 http://dx.doi.org/10.1038/s41541-022-00572-z

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