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Chiral aldehyde-nickel dual catalysis enables asymmetric α−propargylation of amino acids and stereodivergent synthesis of NP25302

The combined catalytic systems derived from organocatalysts and transition metals exhibit powerful activation and stereoselective-control abilities in asymmetric catalysis. This work describes a highly efficient chiral aldehyde-nickel dual catalytic system and its application for the direct asymmetr...

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Detalles Bibliográficos
Autores principales: Zhu, Fang, Li, Chao-Xing, Wu, Zhu-Lian, Cai, Tian, Wen, Wei, Guo, Qi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701212/
https://www.ncbi.nlm.nih.gov/pubmed/36435942
http://dx.doi.org/10.1038/s41467-022-35062-2