Cargando…

GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila

The oncoprotein GOLPH3 (Golgi phosphoprotein 3) is an evolutionarily conserved phosphatidylinositol 4-phosphate effector, mainly localized to the Golgi apparatus, where it supports organelle architecture and vesicular trafficking. Overexpression of human GOLPH3 correlates with poor prognosis in seve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frappaolo, Anna, Karimpour-Ghahnavieh, Angela, Cesare, Giuliana, Sechi, Stefano, Fraschini, Roberta, Vaccari, Thomas, Giansanti, Maria Grazia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701223/ https://www.ncbi.nlm.nih.gov/pubmed/36435842 http://dx.doi.org/10.1038/s41419-022-05438-9

Ejemplares similares

Oncogenic Roles of GOLPH3 in the Physiopathology of Cancer
por: Sechi, Stefano, et al.
Publicado: (2020)

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders
por: Sechi, Stefano, et al.
Publicado: (2021)

The Close Relationship between the Golgi Trafficking Machinery and Protein Glycosylation
por: Frappaolo, Anna, et al.
Publicado: (2020)

Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster
por: Frappaolo, Anna, et al.
Publicado: (2018)

Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster
por: Sechi, Stefano, et al.
Publicado: (2017)

GOLPH3 Is Essential for Contractile Ring Formation and Rab11 Localization to the Cleavage Site during Cytokinesis in Drosophila melanogaster
por: Sechi, Stefano, et al.
Publicado: (2014)

Using Drosophila melanogaster to Dissect the Roles of the mTOR Signaling Pathway in Cell Growth
por: Frappaolo, Anna, et al.
Publicado: (2023)

Cytokinesis in Drosophila male meiosis
por: Giansanti, Maria Grazia, et al.
Publicado: (2012)

Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster
por: Frappaolo, Anna, et al.
Publicado: (2022)

Editorial: Model Organisms: A Precious Resource for the Understanding of Molecular Mechanisms Underlying Human Physiology and Disease
por: Giansanti, Maria Grazia, et al.
Publicado: (2019)

The multiple cellular functions of the oncoprotein Golgi phosphoprotein 3
por: Sechi, Stefano, et al.
Publicado: (2015)

Linking GOLPH3 and Extracellular Vesicles Content—a Potential New Route in Cancer Physiopathology and a Promising Therapeutic Target is in Sight?
por: Giansanti, Maria Grazia, et al.
Publicado: (2022)

Exocyst-Dependent Membrane Addition Is Required for Anaphase Cell Elongation and Cytokinesis in Drosophila
por: Giansanti, Maria Grazia, et al.
Publicado: (2015)

GOLPH3 modulates mTOR signaling and rapamycin sensitivity in cancer
por: Scott, Kenneth L., et al.
Publicado: (2009)

GOLPH3L antagonizes GOLPH3 to determine Golgi morphology
por: Ng, Michelle M., et al.
Publicado: (2013)

Golgi-Related Proteins GOLPH2 (GP73/GOLM1) and GOLPH3 (GOPP1/MIDAS) in Cutaneous Melanoma: Patterns of Expression and Prognostic Significance
por: Donizy, Piotr, et al.
Publicado: (2016)

Golgi Apparatus Target Proteins in Gastroenterological Cancers: A Comprehensive Review of GOLPH3 and GOLGA Proteins
por: Bucurica, Sandica, et al.
Publicado: (2023)

GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles
por: Welch, Lawrence G., et al.
Publicado: (2021)

Expression of GOLPH3 protein in colon cancer tissues and its association with the prognosis of patients
por: Zhou, Bo, et al.
Publicado: (2016)

Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway
por: Liu, Hongying, et al.
Publicado: (2018)

CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer
por: Wu, Wei, et al.
Publicado: (2017)

Minor Kinases with Major Roles in Cytokinesis Regulation
por: Sechi, Stefano, et al.
Publicado: (2022)

Spindle Self-organization and Cytokinesis During Male Meiosis in asterless Mutants of Drosophila melanogaster
por: Bonaccorsi, Silvia, et al.
Publicado: (1998)

GOLPH2 expression in renal cell cancer
por: Fritzsche, Florian Rudolf, et al.
Publicado: (2008)

GOLPH3 keeps the Golgi residents at home
por: Lowe, Martin
Publicado: (2021)

Xenopus as a Model System for the Study of GOLPH2/GP73 Function: Xenopus golph2 Is Required for Pronephros Development
por: Li, Leike, et al.
Publicado: (2012)

STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer
por: Wu, Fan, et al.
Publicado: (2018)

GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics
por: Kristiansen, G, et al.
Publicado: (2008)

Regulation of circGOLPH3 and its binding protein CBX7 on the proliferation and apoptosis of prostate cancer cells
por: Gong, Lifeng, et al.
Publicado: (2020)

Australin: a chromosomal passenger protein required specifically for Drosophila melanogaster male meiosis
por: Gao, Shan, et al.
Publicado: (2008)

GOLPH2 expression may serve as diagnostic marker in seminomas
por: Fritzsche, Florian R, et al.
Publicado: (2010)

Increased Expression of GOLPH3 is Associated with the Proliferation of Prostate Cancer
por: Li, Wenzhi, et al.
Publicado: (2015)

A novel Golgi protein (GOLPH2)-regulated oncolytic adenovirus exhibits potent antitumor efficacy in hepatocellular carcinoma
por: Wang, Yigang, et al.
Publicado: (2015)

The Role of GOLPH3L in the Prognosis and NACT response in Cervical Cancer
por: Feng, Yanling, et al.
Publicado: (2017)

TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila
por: Kim, Ah-Ram, et al.
Publicado: (2019)

GOLPH3 Promotes Cancer Growth by Interacting With STIP1 and Regulating Telomerase Activity in Pancreatic Ductal Adenocarcinoma
por: Wang, Kebing, et al.
Publicado: (2020)

Mechanisms of GOLPH3 Associated with the Progression of Gastric Cancer: A Preliminary Study
por: Peng, Jinzhen, et al.
Publicado: (2014)

GOLPH3L is a Novel Prognostic Biomarker for Epithelial Ovarian Cancer
por: Feng, Yanling, et al.
Publicado: (2015)

The GOLPH3 pathway regulates Golgi shape and function and is activated by DNA damage
por: Buschman, Matthew D., et al.
Publicado: (2015)

Effect of GOLPH3 on cumulus granulosa cell apoptosis and ICSI pregnancy outcomes
por: Lin, Dianliang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8imi82fekgn4v7u9gdft41n9to