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Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1

In chromatin, linker histone H1 binds to nucleosomes, forming chromatosomes, and changes the transcription status. However, the mechanism by which RNA polymerase II (RNAPII) transcribes the DNA in the chromatosome has remained enigmatic. Here we report the cryo-electron microscopy (cryo-EM) structur...

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Detalles Bibliográficos
Autores principales:	Hirano, Rina, Ehara, Haruhiko, Kujirai, Tomoya, Uejima, Tamami, Takizawa, Yoshimasa, Sekine, Shun-ichi, Kurumizaka, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701232/ https://www.ncbi.nlm.nih.gov/pubmed/36435862 http://dx.doi.org/10.1038/s41467-022-35003-z

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