Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report

Adenoid cystic carcinoma (ACC) is a rare epithelial tumor of the salivary glands with an indolent course and usually bears a long-term survival rate even when metastasized. Spontaneous regression of such a resistant tumor is an even scarce event. We report a case of a patient with ACC of the parotid...

Descripción completa

Detalles Bibliográficos
Autores principales: Pokhrel, Bidushi, Chidharla, Anusha, Neupane, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701274/
https://www.ncbi.nlm.nih.gov/pubmed/36447731
http://dx.doi.org/10.7759/cureus.30783
_version_ 1784839497877291008
author Pokhrel, Bidushi
Chidharla, Anusha
Neupane, Prakash
author_facet Pokhrel, Bidushi
Chidharla, Anusha
Neupane, Prakash
author_sort Pokhrel, Bidushi
collection PubMed
description Adenoid cystic carcinoma (ACC) is a rare epithelial tumor of the salivary glands with an indolent course and usually bears a long-term survival rate even when metastasized. Spontaneous regression of such a resistant tumor is an even scarce event. We report a case of a patient with ACC of the parotid gland with pulmonary metastases, which spontaneously resolved following resection and post-surgical radiation of the primary tumor. Among the numerous theories proposed to explain such a phenomenon, immunogenic mechanisms and the abscopal effect are the most plausible explanations in this case.
format Online
Article
Text
id pubmed-9701274
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-97012742022-11-28 Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report Pokhrel, Bidushi Chidharla, Anusha Neupane, Prakash Cureus Radiation Oncology Adenoid cystic carcinoma (ACC) is a rare epithelial tumor of the salivary glands with an indolent course and usually bears a long-term survival rate even when metastasized. Spontaneous regression of such a resistant tumor is an even scarce event. We report a case of a patient with ACC of the parotid gland with pulmonary metastases, which spontaneously resolved following resection and post-surgical radiation of the primary tumor. Among the numerous theories proposed to explain such a phenomenon, immunogenic mechanisms and the abscopal effect are the most plausible explanations in this case. Cureus 2022-10-27 /pmc/articles/PMC9701274/ /pubmed/36447731 http://dx.doi.org/10.7759/cureus.30783 Text en Copyright © 2022, Pokhrel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Pokhrel, Bidushi
Chidharla, Anusha
Neupane, Prakash
Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report
title Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report
title_full Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report
title_fullStr Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report
title_full_unstemmed Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report
title_short Spontaneous Regression of the Pulmonary Metastases in Adenoid Cystic Carcinoma of the Parotid Gland: A Case Report
title_sort spontaneous regression of the pulmonary metastases in adenoid cystic carcinoma of the parotid gland: a case report
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701274/
https://www.ncbi.nlm.nih.gov/pubmed/36447731
http://dx.doi.org/10.7759/cureus.30783
work_keys_str_mv AT pokhrelbidushi spontaneousregressionofthepulmonarymetastasesinadenoidcysticcarcinomaoftheparotidglandacasereport
AT chidharlaanusha spontaneousregressionofthepulmonarymetastasesinadenoidcysticcarcinomaoftheparotidglandacasereport
AT neupaneprakash spontaneousregressionofthepulmonarymetastasesinadenoidcysticcarcinomaoftheparotidglandacasereport

Ejemplares similares