CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin

BACKGROUND: It is highly desirable to develop new therapeutic strategies for gastric cancer given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) is a membrane protein highly expressed in cancers of digestive system. Nanobody represents a novel antibody format for...

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Detalles Bibliográficos
Autores principales: Ma, Jingbo, Xu, Xiaolong, Fu, Chunjin, Xia, Peng, Tian, Ming, Zheng, Liuhai, Chen, Kun, Liu, Xiaolian, Li, Yilei, Yu, Le, Zhu, Qinchang, Yu, Yangyang, Fan, Rongrong, Jiang, Haibo, Li, Zhifen, Yang, Chuanbin, Xu, Chengchao, Long, Ying, Wang, Jigang, Li, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701387/
https://www.ncbi.nlm.nih.gov/pubmed/36435809
http://dx.doi.org/10.1186/s40824-022-00312-3

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