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Tetrandrine inhibits RANKL-induced osteoclastogenesis by promoting the degradation of TRAIL

BACKGROUND: Tetrandrine, a bisbenzylisoquinoline (BBI) alkaloid extracted from Stephania tetrandra (S. Moore), and is widely used in several diseases such as tuberculosis, hyperglycemia, malaria, and tumors. Tetrandrine was recently shown to prevent bone loss in ovariectomized mice. However, the spe...

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Detalles Bibliográficos
Autores principales:	Li, Jiarui, Li, Xiang, Zhou, Shengji, Wang, Yuxin, Lu, Yang, Wang, Quan, Zhao, Fengchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701442/ https://www.ncbi.nlm.nih.gov/pubmed/36435772 http://dx.doi.org/10.1186/s10020-022-00568-4

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