COVID-19-Induced Sporadic Inclusion Body Myositis

Sporadic inclusion body myositis (sIBM) is an autoimmune condition that is characterized by progressive weakness and muscular atrophy in the extremities. The pathophysiology is not exactly clear; however, some studies have postulated an involvement of cytotoxic T cells (CD8+), causing an autoimmune...

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Detalles Bibliográficos
Autores principales: Dalal, Fazal, Dalal, Hussain, McNew, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701533/
https://www.ncbi.nlm.nih.gov/pubmed/36447724
http://dx.doi.org/10.7759/cureus.30808
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author Dalal, Fazal
Dalal, Hussain
McNew, Gina
author_facet Dalal, Fazal
Dalal, Hussain
McNew, Gina
author_sort Dalal, Fazal
collection PubMed
description Sporadic inclusion body myositis (sIBM) is an autoimmune condition that is characterized by progressive weakness and muscular atrophy in the extremities. The pathophysiology is not exactly clear; however, some studies have postulated an involvement of cytotoxic T cells (CD8+), causing an autoimmune response. While the implications of COVID-19 infection are an evolving topic, myositis has been previously implicated in other viral etiologies. We discuss a case of sIBM secondary to COVID-19 in a patient with chronic myalgias bringing to light a rare implication of COVID-19 to educate the medical community. 
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spelling pubmed-97015332022-11-28 COVID-19-Induced Sporadic Inclusion Body Myositis Dalal, Fazal Dalal, Hussain McNew, Gina Cureus Internal Medicine Sporadic inclusion body myositis (sIBM) is an autoimmune condition that is characterized by progressive weakness and muscular atrophy in the extremities. The pathophysiology is not exactly clear; however, some studies have postulated an involvement of cytotoxic T cells (CD8+), causing an autoimmune response. While the implications of COVID-19 infection are an evolving topic, myositis has been previously implicated in other viral etiologies. We discuss a case of sIBM secondary to COVID-19 in a patient with chronic myalgias bringing to light a rare implication of COVID-19 to educate the medical community.  Cureus 2022-10-28 /pmc/articles/PMC9701533/ /pubmed/36447724 http://dx.doi.org/10.7759/cureus.30808 Text en Copyright © 2022, Dalal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Dalal, Fazal
Dalal, Hussain
McNew, Gina
COVID-19-Induced Sporadic Inclusion Body Myositis
title COVID-19-Induced Sporadic Inclusion Body Myositis
title_full COVID-19-Induced Sporadic Inclusion Body Myositis
title_fullStr COVID-19-Induced Sporadic Inclusion Body Myositis
title_full_unstemmed COVID-19-Induced Sporadic Inclusion Body Myositis
title_short COVID-19-Induced Sporadic Inclusion Body Myositis
title_sort covid-19-induced sporadic inclusion body myositis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701533/
https://www.ncbi.nlm.nih.gov/pubmed/36447724
http://dx.doi.org/10.7759/cureus.30808
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AT dalalhussain covid19inducedsporadicinclusionbodymyositis
AT mcnewgina covid19inducedsporadicinclusionbodymyositis

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