Optogenetic induction of hibernation-like state with modified human Opsin4 in mice

We recently determined that the excitatory manipulation of Qrfp-expressing neurons in the preoptic area of the hypothalamus (quiescence-inducing neurons [Q neurons]) induced a hibernation-like hypothermic/hypometabolic state (QIH) in mice. To control the QIH with a higher time resolution, we develop...

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Detalles Bibliográficos
Autores principales: Takahashi, Tohru M., Hirano, Arisa, Kanda, Takeshi, Saito, Viviane M., Ashitomi, Hiroto, Tanaka, Kazumasa Z., Yokoshiki, Yasufumi, Masuda, Kosaku, Yanagisawa, Masashi, Vogt, Kaspar E., Tokuda, Takashi, Sakurai, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701604/
https://www.ncbi.nlm.nih.gov/pubmed/36452866
http://dx.doi.org/10.1016/j.crmeth.2022.100336

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