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A high-throughput electron tomography workflow reveals over-elongated centrioles in relapsed/refractory multiple myeloma

Electron microscopy is the gold standard to characterize centrosomal ultrastructure. However, production of significant morphometrical data is highly limited by acquisition time. We therefore developed a generalizable, semi-automated high-throughput electron tomography strategy to study centrosome a...

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Detalles Bibliográficos
Autores principales:	Dittrich, Tobias, Köhrer, Sebastian, Schorb, Martin, Haberbosch, Isabella, Börmel, Mandy, Goldschmidt, Hartmut, Pajor, Gabor, Müller-Tidow, Carsten, Raab, Marc S., Hegenbart, Ute, Schönland, Stefan O., Schwab, Yannick, Krämer, Alwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701608/ https://www.ncbi.nlm.nih.gov/pubmed/36452870 http://dx.doi.org/10.1016/j.crmeth.2022.100322

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