An optimized Sendai viral vector platform for reprogramming to naive pluripotency

Technologies to reprogram somatic cells into iPSCs have advanced significantly, however challenges to the derivation of iPSCs remain. In this issue of Cell Reports Methods, Kunitomi et al. address some of these challenges by developing a straightforward protocol to derive naive human iPSCs using Sen...

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Detalles Bibliográficos
Autores principales: Charlesworth, Carsten T., Nakauchi, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701616/
https://www.ncbi.nlm.nih.gov/pubmed/36452874
http://dx.doi.org/10.1016/j.crmeth.2022.100349
Descripción
Sumario:Technologies to reprogram somatic cells into iPSCs have advanced significantly, however challenges to the derivation of iPSCs remain. In this issue of Cell Reports Methods, Kunitomi et al. address some of these challenges by developing a straightforward protocol to derive naive human iPSCs using Sendai virus vectors.

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