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Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701678/ https://www.ncbi.nlm.nih.gov/pubmed/36437298 http://dx.doi.org/10.1038/s41598-022-24409-w |
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author | Durier, Christine Ninove, Laetitia Lefebvre, Maeva Radenne, Anne Desaint, Corinne Ropers, Jacques Bauer, Rebecca Lebbah, Said Carette, Diane Lachatre, Marie Lecompte, Anne-Sophie Deplanque, Dominique Botelho-Nevers, Elisabeth Conrad, Anne Dussol, Bertrand Maakaroun-Vermesse, Zoha Melica, Giovanna Nicolas, Jean-François Verdon, Renaud Kiladjian, Jacques Loubet, Paul Schmidt-Mutter, Catherine Dualé, Christian Ansart, Séverine Priet, Stéphane Levier, Axel Molino, Diana Vieillard, Louis-Victorien Parfait, Béatrice Lelièvre, Jean-Daniel Tartour, Eric de Lamballerie, Xavier Launay, Odile |
author_facet | Durier, Christine Ninove, Laetitia Lefebvre, Maeva Radenne, Anne Desaint, Corinne Ropers, Jacques Bauer, Rebecca Lebbah, Said Carette, Diane Lachatre, Marie Lecompte, Anne-Sophie Deplanque, Dominique Botelho-Nevers, Elisabeth Conrad, Anne Dussol, Bertrand Maakaroun-Vermesse, Zoha Melica, Giovanna Nicolas, Jean-François Verdon, Renaud Kiladjian, Jacques Loubet, Paul Schmidt-Mutter, Catherine Dualé, Christian Ansart, Séverine Priet, Stéphane Levier, Axel Molino, Diana Vieillard, Louis-Victorien Parfait, Béatrice Lelièvre, Jean-Daniel Tartour, Eric de Lamballerie, Xavier Launay, Odile |
author_sort | Durier, Christine |
collection | PubMed |
description | Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost. |
format | Online Article Text |
id | pubmed-9701678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-97016782022-11-28 Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years Durier, Christine Ninove, Laetitia Lefebvre, Maeva Radenne, Anne Desaint, Corinne Ropers, Jacques Bauer, Rebecca Lebbah, Said Carette, Diane Lachatre, Marie Lecompte, Anne-Sophie Deplanque, Dominique Botelho-Nevers, Elisabeth Conrad, Anne Dussol, Bertrand Maakaroun-Vermesse, Zoha Melica, Giovanna Nicolas, Jean-François Verdon, Renaud Kiladjian, Jacques Loubet, Paul Schmidt-Mutter, Catherine Dualé, Christian Ansart, Séverine Priet, Stéphane Levier, Axel Molino, Diana Vieillard, Louis-Victorien Parfait, Béatrice Lelièvre, Jean-Daniel Tartour, Eric de Lamballerie, Xavier Launay, Odile Sci Rep Article Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost. Nature Publishing Group UK 2022-11-27 /pmc/articles/PMC9701678/ /pubmed/36437298 http://dx.doi.org/10.1038/s41598-022-24409-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Durier, Christine Ninove, Laetitia Lefebvre, Maeva Radenne, Anne Desaint, Corinne Ropers, Jacques Bauer, Rebecca Lebbah, Said Carette, Diane Lachatre, Marie Lecompte, Anne-Sophie Deplanque, Dominique Botelho-Nevers, Elisabeth Conrad, Anne Dussol, Bertrand Maakaroun-Vermesse, Zoha Melica, Giovanna Nicolas, Jean-François Verdon, Renaud Kiladjian, Jacques Loubet, Paul Schmidt-Mutter, Catherine Dualé, Christian Ansart, Séverine Priet, Stéphane Levier, Axel Molino, Diana Vieillard, Louis-Victorien Parfait, Béatrice Lelièvre, Jean-Daniel Tartour, Eric de Lamballerie, Xavier Launay, Odile Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
title | Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
title_full | Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
title_fullStr | Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
title_full_unstemmed | Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
title_short | Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
title_sort | neutralizing antibodies against sars-cov-2 variants following mrna booster vaccination in adults older than 65 years |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701678/ https://www.ncbi.nlm.nih.gov/pubmed/36437298 http://dx.doi.org/10.1038/s41598-022-24409-w |
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