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Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years

Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related...

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Autores principales: Durier, Christine, Ninove, Laetitia, Lefebvre, Maeva, Radenne, Anne, Desaint, Corinne, Ropers, Jacques, Bauer, Rebecca, Lebbah, Said, Carette, Diane, Lachatre, Marie, Lecompte, Anne-Sophie, Deplanque, Dominique, Botelho-Nevers, Elisabeth, Conrad, Anne, Dussol, Bertrand, Maakaroun-Vermesse, Zoha, Melica, Giovanna, Nicolas, Jean-François, Verdon, Renaud, Kiladjian, Jacques, Loubet, Paul, Schmidt-Mutter, Catherine, Dualé, Christian, Ansart, Séverine, Priet, Stéphane, Levier, Axel, Molino, Diana, Vieillard, Louis-Victorien, Parfait, Béatrice, Lelièvre, Jean-Daniel, Tartour, Eric, de Lamballerie, Xavier, Launay, Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701678/
https://www.ncbi.nlm.nih.gov/pubmed/36437298
http://dx.doi.org/10.1038/s41598-022-24409-w
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author Durier, Christine
Ninove, Laetitia
Lefebvre, Maeva
Radenne, Anne
Desaint, Corinne
Ropers, Jacques
Bauer, Rebecca
Lebbah, Said
Carette, Diane
Lachatre, Marie
Lecompte, Anne-Sophie
Deplanque, Dominique
Botelho-Nevers, Elisabeth
Conrad, Anne
Dussol, Bertrand
Maakaroun-Vermesse, Zoha
Melica, Giovanna
Nicolas, Jean-François
Verdon, Renaud
Kiladjian, Jacques
Loubet, Paul
Schmidt-Mutter, Catherine
Dualé, Christian
Ansart, Séverine
Priet, Stéphane
Levier, Axel
Molino, Diana
Vieillard, Louis-Victorien
Parfait, Béatrice
Lelièvre, Jean-Daniel
Tartour, Eric
de Lamballerie, Xavier
Launay, Odile
author_facet Durier, Christine
Ninove, Laetitia
Lefebvre, Maeva
Radenne, Anne
Desaint, Corinne
Ropers, Jacques
Bauer, Rebecca
Lebbah, Said
Carette, Diane
Lachatre, Marie
Lecompte, Anne-Sophie
Deplanque, Dominique
Botelho-Nevers, Elisabeth
Conrad, Anne
Dussol, Bertrand
Maakaroun-Vermesse, Zoha
Melica, Giovanna
Nicolas, Jean-François
Verdon, Renaud
Kiladjian, Jacques
Loubet, Paul
Schmidt-Mutter, Catherine
Dualé, Christian
Ansart, Séverine
Priet, Stéphane
Levier, Axel
Molino, Diana
Vieillard, Louis-Victorien
Parfait, Béatrice
Lelièvre, Jean-Daniel
Tartour, Eric
de Lamballerie, Xavier
Launay, Odile
author_sort Durier, Christine
collection PubMed
description Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.
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spelling pubmed-97016782022-11-28 Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years Durier, Christine Ninove, Laetitia Lefebvre, Maeva Radenne, Anne Desaint, Corinne Ropers, Jacques Bauer, Rebecca Lebbah, Said Carette, Diane Lachatre, Marie Lecompte, Anne-Sophie Deplanque, Dominique Botelho-Nevers, Elisabeth Conrad, Anne Dussol, Bertrand Maakaroun-Vermesse, Zoha Melica, Giovanna Nicolas, Jean-François Verdon, Renaud Kiladjian, Jacques Loubet, Paul Schmidt-Mutter, Catherine Dualé, Christian Ansart, Séverine Priet, Stéphane Levier, Axel Molino, Diana Vieillard, Louis-Victorien Parfait, Béatrice Lelièvre, Jean-Daniel Tartour, Eric de Lamballerie, Xavier Launay, Odile Sci Rep Article Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65–84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost. Nature Publishing Group UK 2022-11-27 /pmc/articles/PMC9701678/ /pubmed/36437298 http://dx.doi.org/10.1038/s41598-022-24409-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Durier, Christine
Ninove, Laetitia
Lefebvre, Maeva
Radenne, Anne
Desaint, Corinne
Ropers, Jacques
Bauer, Rebecca
Lebbah, Said
Carette, Diane
Lachatre, Marie
Lecompte, Anne-Sophie
Deplanque, Dominique
Botelho-Nevers, Elisabeth
Conrad, Anne
Dussol, Bertrand
Maakaroun-Vermesse, Zoha
Melica, Giovanna
Nicolas, Jean-François
Verdon, Renaud
Kiladjian, Jacques
Loubet, Paul
Schmidt-Mutter, Catherine
Dualé, Christian
Ansart, Séverine
Priet, Stéphane
Levier, Axel
Molino, Diana
Vieillard, Louis-Victorien
Parfait, Béatrice
Lelièvre, Jean-Daniel
Tartour, Eric
de Lamballerie, Xavier
Launay, Odile
Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
title Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
title_full Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
title_fullStr Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
title_full_unstemmed Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
title_short Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
title_sort neutralizing antibodies against sars-cov-2 variants following mrna booster vaccination in adults older than 65 years
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701678/
https://www.ncbi.nlm.nih.gov/pubmed/36437298
http://dx.doi.org/10.1038/s41598-022-24409-w
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