High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection

The COVID-19 course and immunity differ in children and adults. We analyzed immune response dynamics in 28 families up to 12 months after mild or asymptomatic infection. Unlike adults, the initial response is plasmablast-driven in children. Four months after infection, children show an enhanced spec...

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Detalles Bibliográficos
Autores principales: Jacobsen, Eva-Maria, Fabricius, Dorit, Class, Magdalena, Topfstedt, Fernando, Lorenzetti, Raquel, Janowska, Iga, Schmidt, Franziska, Staniek, Julian, Zernickel, Maria, Stamminger, Thomas, Dietz, Andrea N., Zellmer, Angela, Hecht, Manuel, Rauch, Peter, Blum, Carmen, Ludwig, Carolin, Jahrsdörfer, Bernd, Schrezenmeier, Hubert, Heeg, Maximilian, Mayer, Benjamin, Seidel, Alina, Groß, Rüdiger, Münch, Jan, Kirchhoff, Frank, Bode, Sebastian F. N., Strauss, Gudrun, Renk, Hanna, Elling, Roland, Stich, Maximillian, Voll, Reinhard E., Tönshof, Burkhard, Franz, Axel R., Henneke, Philipp, Debatin, Klaus-Michael, Rizzi, Marta, Janda, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701757/
https://www.ncbi.nlm.nih.gov/pubmed/36437276
http://dx.doi.org/10.1038/s41467-022-35055-1

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