Cargando…
The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19
BACKGROUND: Novel coronavirus (COVID‐19) pandemic has become a global concern and requires early detection, isolation, and treatment. Our purpose is to find some beneficial information by analyzing the COVID‐19 laboratory data to provide guidance for clinical practice. MATERIAL AND METHODS: In this...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701842/ https://www.ncbi.nlm.nih.gov/pubmed/36245411 http://dx.doi.org/10.1002/jcla.24713 |
_version_ | 1784839629627719680 |
---|---|
author | Ghaznavi‐Rad, Ehsanollah Khosravi, Mahmood Sayyadi, Mohammad |
author_facet | Ghaznavi‐Rad, Ehsanollah Khosravi, Mahmood Sayyadi, Mohammad |
author_sort | Ghaznavi‐Rad, Ehsanollah |
collection | PubMed |
description | BACKGROUND: Novel coronavirus (COVID‐19) pandemic has become a global concern and requires early detection, isolation, and treatment. Our purpose is to find some beneficial information by analyzing the COVID‐19 laboratory data to provide guidance for clinical practice. MATERIAL AND METHODS: In this study, 174 patients with confirmed COVID‐19 infection were admitted. We evaluated the hematological and biochemical parameters in these patients and in 80 healthy individuals. RESULTS: We found that there was significant difference between WBC, LYM, RBC, HB, and HCT parameters of patients and healthy counterparts (p < .001), though there was no remarkable change between NEU, MONO, PLT, and other characteristics of RBC values of patients and the control group (p ≥ .09). Among the evaluated biochemical parameters, the values of CK‐MB and LDH in the patient group were significantly different from the control group (p < .01), while other biochemical indicators were in the normal range. CONCLUSION: Several hematological and biochemistry parameters, in particular WBC, LYM, RBC, HB, HCT, CK‐MB, and LDH, could be beneficial supplementary approach for COVID‐19 infection evaluation to confirm risk stratification and effective management. |
format | Online Article Text |
id | pubmed-9701842 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97018422022-11-28 The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 Ghaznavi‐Rad, Ehsanollah Khosravi, Mahmood Sayyadi, Mohammad J Clin Lab Anal Research Articles BACKGROUND: Novel coronavirus (COVID‐19) pandemic has become a global concern and requires early detection, isolation, and treatment. Our purpose is to find some beneficial information by analyzing the COVID‐19 laboratory data to provide guidance for clinical practice. MATERIAL AND METHODS: In this study, 174 patients with confirmed COVID‐19 infection were admitted. We evaluated the hematological and biochemical parameters in these patients and in 80 healthy individuals. RESULTS: We found that there was significant difference between WBC, LYM, RBC, HB, and HCT parameters of patients and healthy counterparts (p < .001), though there was no remarkable change between NEU, MONO, PLT, and other characteristics of RBC values of patients and the control group (p ≥ .09). Among the evaluated biochemical parameters, the values of CK‐MB and LDH in the patient group were significantly different from the control group (p < .01), while other biochemical indicators were in the normal range. CONCLUSION: Several hematological and biochemistry parameters, in particular WBC, LYM, RBC, HB, HCT, CK‐MB, and LDH, could be beneficial supplementary approach for COVID‐19 infection evaluation to confirm risk stratification and effective management. John Wiley and Sons Inc. 2022-10-17 /pmc/articles/PMC9701842/ /pubmed/36245411 http://dx.doi.org/10.1002/jcla.24713 Text en © 2022 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Ghaznavi‐Rad, Ehsanollah Khosravi, Mahmood Sayyadi, Mohammad The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 |
title | The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 |
title_full | The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 |
title_fullStr | The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 |
title_full_unstemmed | The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 |
title_short | The importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: Shedding light on clinical laboratory data in COVID‐19 |
title_sort | importance of using routine laboratory tests in the diagnosis and prognosis of patients with coronavirus disease 2019: shedding light on clinical laboratory data in covid‐19 |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701842/ https://www.ncbi.nlm.nih.gov/pubmed/36245411 http://dx.doi.org/10.1002/jcla.24713 |
work_keys_str_mv | AT ghaznaviradehsanollah theimportanceofusingroutinelaboratorytestsinthediagnosisandprognosisofpatientswithcoronavirusdisease2019sheddinglightonclinicallaboratorydataincovid19 AT khosravimahmood theimportanceofusingroutinelaboratorytestsinthediagnosisandprognosisofpatientswithcoronavirusdisease2019sheddinglightonclinicallaboratorydataincovid19 AT sayyadimohammad theimportanceofusingroutinelaboratorytestsinthediagnosisandprognosisofpatientswithcoronavirusdisease2019sheddinglightonclinicallaboratorydataincovid19 AT ghaznaviradehsanollah importanceofusingroutinelaboratorytestsinthediagnosisandprognosisofpatientswithcoronavirusdisease2019sheddinglightonclinicallaboratorydataincovid19 AT khosravimahmood importanceofusingroutinelaboratorytestsinthediagnosisandprognosisofpatientswithcoronavirusdisease2019sheddinglightonclinicallaboratorydataincovid19 AT sayyadimohammad importanceofusingroutinelaboratorytestsinthediagnosisandprognosisofpatientswithcoronavirusdisease2019sheddinglightonclinicallaboratorydataincovid19 |