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Back to basic: Trials and tribulations of alkalizing agents in cancer
“Dysregulated” metabolism is a characteristic of the cancer cell phenotype. This includes persistent use of glycolytic metabolism in normoxic environments (Warburg effect) leading to increased acid production and accumulation of protons in the interstitial space. Although often thought to be disorde...
Autores principales: | Gillies, Robert J., Ibrahim-Hashim, Arig, Ordway, Bryce, Gatenby, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702334/ https://www.ncbi.nlm.nih.gov/pubmed/36452492 http://dx.doi.org/10.3389/fonc.2022.981718 |
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