Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease characterized by demyelination and neurodegeneration, for which traditional treatment offers limited relief. Microglial/macrophage modulation plays a critical role in the pathogenesis of MS. Oxygen free radical accumulation can ind...

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Detalles Bibliográficos
Autores principales: Li, Li, Deng, Shihua, Liu, Mingquan, Yang, Min, Li, Jin, Liu, Teng, Zhang, Ting, Zhao, Yangyang, He, Miao, Wu, Dongming, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702353/
https://www.ncbi.nlm.nih.gov/pubmed/36452219
http://dx.doi.org/10.3389/fphar.2022.956402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702353/
https://www.ncbi.nlm.nih.gov/pubmed/36452219
http://dx.doi.org/10.3389/fphar.2022.956402

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