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Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after...

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Detalles Bibliográficos
Autores principales:	Hollidge, Bradley S., Carroll, Hayley B., Qian, Randolph, Fuller, Madison L., Giles, April R., Mercer, Andrew C., Danos, Olivier, Liu, Ye, Bruder, Joseph T., Smith, Jared B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702554/ https://www.ncbi.nlm.nih.gov/pubmed/36452163 http://dx.doi.org/10.3389/fneur.2022.1051559

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