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Age-dependent effect of the IFIH1/MDA5 gene variants on the risk of critical COVID-19

MDA5, encoded by the IFIH1gene, is a cytoplasmic sensor of viral RNAs that triggers interferon (IFN) antiviral responses. Common and rare IFIH1 variants have been associated with the risk of type 1 diabetes and other immune-mediated disorders, and with the outcome of viral diseases. Variants associa...

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Detalles Bibliográficos
Autores principales:	Muñiz-Banciella, María G., Albaiceta, Guillermo M., Amado-Rodríguez, Laura, del Riego, Estefanía Salgado, Alonso, Inés López, López-Martínez, Cecilia, Martín-Vicente, Paula, García-Clemente, Marta, Hermida-Valverde, Tamara, Enríquez-Rodriguez, Ana I., Hernández-González, Cristina, Cuesta-Llavona, Elías, Alvarez, Victoria, Gómez, Juan, Coto, Eliecer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702716/ https://www.ncbi.nlm.nih.gov/pubmed/36434151 http://dx.doi.org/10.1007/s00251-022-01281-6

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