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Identification of FDA-approved drugs against SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through computational virtual screening

The SARS-CoV-2 coronavirus is responsible for the COVID-19 outbreak, which overwhelmed millions of people worldwide; hence, there is an urgency to identify appropriate antiviral drugs. This study focuses on screening compounds that inhibit RNA-dependent RNA-polymerase (RdRp) essential for RNA synthe...

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Detalles Bibliográficos
Autores principales:	Jade, Dhananjay, Alzahrani, Areej, Critchley, William, Ponnambalam, Sreenivasan, Harrison, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702953/ https://www.ncbi.nlm.nih.gov/pubmed/36467260 http://dx.doi.org/10.1007/s11224-022-02072-1

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