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The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703004/ https://www.ncbi.nlm.nih.gov/pubmed/36474750 http://dx.doi.org/10.1016/j.ncrna.2022.11.004 |
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author | Sufianov, Albert Begliarzade, Sema Kudriashov, Valentin Beilerli, Aferin Ilyasova, Tatiana Liang, Yanchao Beylerli, Ozal |
author_facet | Sufianov, Albert Begliarzade, Sema Kudriashov, Valentin Beilerli, Aferin Ilyasova, Tatiana Liang, Yanchao Beylerli, Ozal |
author_sort | Sufianov, Albert |
collection | PubMed |
description | Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence and development of diseases and has a potential to be used as a disease marker. Oral squamous cell carcinoma is one of the most common malignant tumors in oral surgery. It is difficult to treat, easy to metastasize, and has a poor prognosis. Due to its unclear mechanism, blocking oral squamous cell carcinoma at the genetic level cannot be achieved. The research progress of circular RNA in the field of oral squamous cell carcinoma will bring new ideas for the biological treatment of oral squamous cell carcinoma. This review summarizes the circRNAs mechanism, the biological function and the research progress in the development of tumors, especially oral squamous cell carcinoma. |
format | Online Article Text |
id | pubmed-9703004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-97030042022-12-05 The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma Sufianov, Albert Begliarzade, Sema Kudriashov, Valentin Beilerli, Aferin Ilyasova, Tatiana Liang, Yanchao Beylerli, Ozal Noncoding RNA Res Review Article Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence and development of diseases and has a potential to be used as a disease marker. Oral squamous cell carcinoma is one of the most common malignant tumors in oral surgery. It is difficult to treat, easy to metastasize, and has a poor prognosis. Due to its unclear mechanism, blocking oral squamous cell carcinoma at the genetic level cannot be achieved. The research progress of circular RNA in the field of oral squamous cell carcinoma will bring new ideas for the biological treatment of oral squamous cell carcinoma. This review summarizes the circRNAs mechanism, the biological function and the research progress in the development of tumors, especially oral squamous cell carcinoma. KeAi Publishing 2022-11-22 /pmc/articles/PMC9703004/ /pubmed/36474750 http://dx.doi.org/10.1016/j.ncrna.2022.11.004 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Article Sufianov, Albert Begliarzade, Sema Kudriashov, Valentin Beilerli, Aferin Ilyasova, Tatiana Liang, Yanchao Beylerli, Ozal The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma |
title | The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma |
title_full | The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma |
title_fullStr | The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma |
title_full_unstemmed | The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma |
title_short | The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma |
title_sort | role of circular rnas in the pathophysiology of oral squamous cell carcinoma |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703004/ https://www.ncbi.nlm.nih.gov/pubmed/36474750 http://dx.doi.org/10.1016/j.ncrna.2022.11.004 |
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