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The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma

Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence...

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Autores principales: Sufianov, Albert, Begliarzade, Sema, Kudriashov, Valentin, Beilerli, Aferin, Ilyasova, Tatiana, Liang, Yanchao, Beylerli, Ozal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703004/
https://www.ncbi.nlm.nih.gov/pubmed/36474750
http://dx.doi.org/10.1016/j.ncrna.2022.11.004
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author Sufianov, Albert
Begliarzade, Sema
Kudriashov, Valentin
Beilerli, Aferin
Ilyasova, Tatiana
Liang, Yanchao
Beylerli, Ozal
author_facet Sufianov, Albert
Begliarzade, Sema
Kudriashov, Valentin
Beilerli, Aferin
Ilyasova, Tatiana
Liang, Yanchao
Beylerli, Ozal
author_sort Sufianov, Albert
collection PubMed
description Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence and development of diseases and has a potential to be used as a disease marker. Oral squamous cell carcinoma is one of the most common malignant tumors in oral surgery. It is difficult to treat, easy to metastasize, and has a poor prognosis. Due to its unclear mechanism, blocking oral squamous cell carcinoma at the genetic level cannot be achieved. The research progress of circular RNA in the field of oral squamous cell carcinoma will bring new ideas for the biological treatment of oral squamous cell carcinoma. This review summarizes the circRNAs mechanism, the biological function and the research progress in the development of tumors, especially oral squamous cell carcinoma.
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spelling pubmed-97030042022-12-05 The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma Sufianov, Albert Begliarzade, Sema Kudriashov, Valentin Beilerli, Aferin Ilyasova, Tatiana Liang, Yanchao Beylerli, Ozal Noncoding RNA Res Review Article Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence and development of diseases and has a potential to be used as a disease marker. Oral squamous cell carcinoma is one of the most common malignant tumors in oral surgery. It is difficult to treat, easy to metastasize, and has a poor prognosis. Due to its unclear mechanism, blocking oral squamous cell carcinoma at the genetic level cannot be achieved. The research progress of circular RNA in the field of oral squamous cell carcinoma will bring new ideas for the biological treatment of oral squamous cell carcinoma. This review summarizes the circRNAs mechanism, the biological function and the research progress in the development of tumors, especially oral squamous cell carcinoma. KeAi Publishing 2022-11-22 /pmc/articles/PMC9703004/ /pubmed/36474750 http://dx.doi.org/10.1016/j.ncrna.2022.11.004 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Sufianov, Albert
Begliarzade, Sema
Kudriashov, Valentin
Beilerli, Aferin
Ilyasova, Tatiana
Liang, Yanchao
Beylerli, Ozal
The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
title The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
title_full The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
title_fullStr The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
title_full_unstemmed The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
title_short The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma
title_sort role of circular rnas in the pathophysiology of oral squamous cell carcinoma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703004/
https://www.ncbi.nlm.nih.gov/pubmed/36474750
http://dx.doi.org/10.1016/j.ncrna.2022.11.004
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