Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy

With recent advances in oncology, immune checkpoint inhibitors (ICIs) have become a milestone in immuno-oncology. Unfortunately, although ICIs have demonstrated improved clinical efficacy in a broad spectrum of cancers, many patients do not respond to this newer therapy. As a result, it is crucial t...

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Detalles Bibliográficos
Autores principales: Parosanu, Andreea, Stanciu, Ioana Miruna, Pirlog, Cristina, Orlov Slavu, Cristina, Cotan, Horia, Iaciu, Cristian, Popa, Ana Maria, Olaru, Mihaela, Moldoveanu, Oana, Catalin, Baston, Nitipir, Cornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Urology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703028/
https://www.ncbi.nlm.nih.gov/pubmed/36451642
http://dx.doi.org/10.7759/cureus.30821
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author Parosanu, Andreea
Stanciu, Ioana Miruna
Pirlog, Cristina
Orlov Slavu, Cristina
Cotan, Horia
Iaciu, Cristian
Popa, Ana Maria
Olaru, Mihaela
Moldoveanu, Oana
Catalin, Baston
Nitipir, Cornelia
author_facet Parosanu, Andreea
Stanciu, Ioana Miruna
Pirlog, Cristina
Orlov Slavu, Cristina
Cotan, Horia
Iaciu, Cristian
Popa, Ana Maria
Olaru, Mihaela
Moldoveanu, Oana
Catalin, Baston
Nitipir, Cornelia
author_sort Parosanu, Andreea
collection PubMed
description With recent advances in oncology, immune checkpoint inhibitors (ICIs) have become a milestone in immuno-oncology. Unfortunately, although ICIs have demonstrated improved clinical efficacy in a broad spectrum of cancers, many patients do not respond to this newer therapy. As a result, it is crucial to identify predictive factors of response to immunotherapy in patients with kidney cancer. This review discusses the research investigating potential biomarkers of response to ICIs in renal cell carcinoma.
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spelling pubmed-97030282022-11-29 Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy Parosanu, Andreea Stanciu, Ioana Miruna Pirlog, Cristina Orlov Slavu, Cristina Cotan, Horia Iaciu, Cristian Popa, Ana Maria Olaru, Mihaela Moldoveanu, Oana Catalin, Baston Nitipir, Cornelia Cureus Urology With recent advances in oncology, immune checkpoint inhibitors (ICIs) have become a milestone in immuno-oncology. Unfortunately, although ICIs have demonstrated improved clinical efficacy in a broad spectrum of cancers, many patients do not respond to this newer therapy. As a result, it is crucial to identify predictive factors of response to immunotherapy in patients with kidney cancer. This review discusses the research investigating potential biomarkers of response to ICIs in renal cell carcinoma. Cureus 2022-10-29 /pmc/articles/PMC9703028/ /pubmed/36451642 http://dx.doi.org/10.7759/cureus.30821 Text en Copyright © 2022, Parosanu et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Urology
Parosanu, Andreea
Stanciu, Ioana Miruna
Pirlog, Cristina
Orlov Slavu, Cristina
Cotan, Horia
Iaciu, Cristian
Popa, Ana Maria
Olaru, Mihaela
Moldoveanu, Oana
Catalin, Baston
Nitipir, Cornelia
Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy
title Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy
title_full Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy
title_fullStr Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy
title_full_unstemmed Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy
title_short Prognostic Models for Renal Cell Carcinoma in the Era of Immune Checkpoint Therapy
title_sort prognostic models for renal cell carcinoma in the era of immune checkpoint therapy
topic Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703028/
https://www.ncbi.nlm.nih.gov/pubmed/36451642
http://dx.doi.org/10.7759/cureus.30821
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