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Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis
Neurosyphilis is a chronic infectious disease caused by the invasion of Treponema pallidum into the central nervous system. In recent years, with the increase in the latent syphilis infection rate, the incidence of neurosyphilis has gradually increased, the typical symptoms of neurosyphilis have dec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703065/ https://www.ncbi.nlm.nih.gov/pubmed/36452956 http://dx.doi.org/10.3389/fpubh.2022.1030480 |
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author | Gao, Zheng-Xiang Gou, Yu Liu, Xiao-Qin Peng, Lei-Wen |
author_facet | Gao, Zheng-Xiang Gou, Yu Liu, Xiao-Qin Peng, Lei-Wen |
author_sort | Gao, Zheng-Xiang |
collection | PubMed |
description | Neurosyphilis is a chronic infectious disease caused by the invasion of Treponema pallidum into the central nervous system. In recent years, with the increase in the latent syphilis infection rate, the incidence of neurosyphilis has gradually increased, the typical symptoms of neurosyphilis have decreased, atypical manifestations have increased, and the clinical manifestations have become increasingly diverse. Cerebrospinal fluid testing plays an important role in the diagnosis of neurosyphilis. In recent years, there have been many advances in cerebrospinal fluid testing. This review focuses on the current and potential laboratory indicators of neurosyphilis in cerebrospinal fluid, aiming to provide a reference for clinical application and ideas for future experimental research of neurosyphilis. |
format | Online Article Text |
id | pubmed-9703065 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97030652022-11-29 Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis Gao, Zheng-Xiang Gou, Yu Liu, Xiao-Qin Peng, Lei-Wen Front Public Health Public Health Neurosyphilis is a chronic infectious disease caused by the invasion of Treponema pallidum into the central nervous system. In recent years, with the increase in the latent syphilis infection rate, the incidence of neurosyphilis has gradually increased, the typical symptoms of neurosyphilis have decreased, atypical manifestations have increased, and the clinical manifestations have become increasingly diverse. Cerebrospinal fluid testing plays an important role in the diagnosis of neurosyphilis. In recent years, there have been many advances in cerebrospinal fluid testing. This review focuses on the current and potential laboratory indicators of neurosyphilis in cerebrospinal fluid, aiming to provide a reference for clinical application and ideas for future experimental research of neurosyphilis. Frontiers Media S.A. 2022-11-14 /pmc/articles/PMC9703065/ /pubmed/36452956 http://dx.doi.org/10.3389/fpubh.2022.1030480 Text en Copyright © 2022 Gao, Gou, Liu and Peng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Gao, Zheng-Xiang Gou, Yu Liu, Xiao-Qin Peng, Lei-Wen Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
title | Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
title_full | Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
title_fullStr | Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
title_full_unstemmed | Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
title_short | Advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
title_sort | advances in laboratory diagnostic methods for cerebrospinal fluid testing for neurosyphilis |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703065/ https://www.ncbi.nlm.nih.gov/pubmed/36452956 http://dx.doi.org/10.3389/fpubh.2022.1030480 |
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