mTORC2 Facilitates Liver Regeneration Through Sphingolipid-Induced PPAR-α-Fatty Acid Oxidation

BACKGROUND & AIMS: During liver regeneration after partial hepatectomy, the function and metabolic pathways governing transient lipid droplet accumulation in hepatocytes remain obscure. Mammalian target of rapamycin 2 (mTORC2) facilitates de novo synthesis of hepatic lipids. Under normal conditi...

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Detalles Bibliográficos
Autores principales: Zhang, Lingling, Li, Yanqiu, Wang, Ying, Qiu, Yugang, Mou, Hanchuan, Deng, Yuanyao, Yao, Jiyuan, Xia, Zhiqing, Zhang, Wenzhe, Zhu, Di, Qiu, Zeyu, Lu, Zhongjie, Wang, Jirong, Yang, Zhouxin, Mao, GenXiang, Chen, Dan, Sun, Leimin, Liu, Leiming, Ju, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703135/
https://www.ncbi.nlm.nih.gov/pubmed/35931382
http://dx.doi.org/10.1016/j.jcmgh.2022.07.011

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