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Interferon-γ release assay screening in biologics: safe and reliable, but not perfect

BACKGROUND: Systemic biologic agents can increase the risk of re-activation of latent tuberculosis (TB). Prior to initiation, screening for latent TB using an interferon-γ release assay (IGRA) is recommended. There is concern that false-negative IGRAs may be more likely in this context. METHODS: Thi...

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Detalles Bibliográficos
Autores principales: Cafferkey, John, Padayachee, Yorissa, Kostich, Sophia, Kumar, Kartik, Jewell, Paul, Patel, Mikin, Chavda, Aneeka, Cox, Alison, Park, Mirae, Russell, Georgina, Coleman, Meg, Martin, Laura, Kon, Onn Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703145/
https://www.ncbi.nlm.nih.gov/pubmed/36451845
http://dx.doi.org/10.1183/23120541.00193-2022