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Approximate Bayesian computation design for phase I clinical trials

In the development of new cancer treatment, an essential step is to determine the maximum tolerated dose in a phase I clinical trial. In general, phase I trial designs can be classified as either model-based or algorithm-based approaches. Model-based phase I designs are typically more efficient by u...

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Detalles Bibliográficos
Autores principales: Jin, Huaqing, Du, Wenbin, Yin, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703391/
https://www.ncbi.nlm.nih.gov/pubmed/36031856
http://dx.doi.org/10.1177/09622802221122402