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Chirurgie des alten Menschen – Thoraxchirurgie
BACKGROUND: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures. OBJECTIVE: Overview of the current relevant literature, der...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Medizin
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703435/ https://www.ncbi.nlm.nih.gov/pubmed/36441200 http://dx.doi.org/10.1007/s00104-022-01772-y |
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author | Ehrsam, Jonas Peter Aigner, Clemens |
author_facet | Ehrsam, Jonas Peter Aigner, Clemens |
author_sort | Ehrsam, Jonas Peter |
collection | PubMed |
description | BACKGROUND: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures. OBJECTIVE: Overview of the current relevant literature, derivation of recommendations for patient selection as well as preoperative, perioperative and postoperative optimization. MATERIAL AND METHODS: Analysis of the current study situation. RESULTS: Recent data show that for most thoracic diseases, age alone is not a reason to withhold surgical treatment. Much more important for the selection are comorbidities, frailty, malnutrition and cognitive impairment. A lobectomy or segmentectomy for stage I non-small cell lung cancer (NSCLC) in carefully selected octogenarians can provide acceptable to even comparably good short-term and long-term results as in younger patients. Selected > 75-year-old patients with stages II-IIIA NSCLC even benefit from adjuvant chemotherapy. With appropriate selection high-risk interventions, such as pneumonectomy in > 70-year-old patients and pulmonary endarterectomy in > 80-year-old patients can be performed without an increase in mortality rates. Even lung transplantation can lead to good long-term results in carefully selected > 70-year-old patients. Minimally invasive surgical techniques and nonintubated anesthesia contribute to risk reduction in marginal patients. DISCUSSION: In thoracic surgery the biological age rather than the chronological age is decisive. In view of the increasingly older population, further studies are urgently needed to optimize patient selection, type of intervention, preoperative planning and postoperative treatment as well as the quality of life. |
format | Online Article Text |
id | pubmed-9703435 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Medizin |
record_format | MEDLINE/PubMed |
spelling | pubmed-97034352022-11-28 Chirurgie des alten Menschen – Thoraxchirurgie Ehrsam, Jonas Peter Aigner, Clemens Chirurgie (Heidelb) Leitthema BACKGROUND: The incidence of a large number of diseases relevant to thoracic surgery increases with age; however, old age is still frequently considered a contraindication per se for curative interventions and extensive surgical procedures. OBJECTIVE: Overview of the current relevant literature, derivation of recommendations for patient selection as well as preoperative, perioperative and postoperative optimization. MATERIAL AND METHODS: Analysis of the current study situation. RESULTS: Recent data show that for most thoracic diseases, age alone is not a reason to withhold surgical treatment. Much more important for the selection are comorbidities, frailty, malnutrition and cognitive impairment. A lobectomy or segmentectomy for stage I non-small cell lung cancer (NSCLC) in carefully selected octogenarians can provide acceptable to even comparably good short-term and long-term results as in younger patients. Selected > 75-year-old patients with stages II-IIIA NSCLC even benefit from adjuvant chemotherapy. With appropriate selection high-risk interventions, such as pneumonectomy in > 70-year-old patients and pulmonary endarterectomy in > 80-year-old patients can be performed without an increase in mortality rates. Even lung transplantation can lead to good long-term results in carefully selected > 70-year-old patients. Minimally invasive surgical techniques and nonintubated anesthesia contribute to risk reduction in marginal patients. DISCUSSION: In thoracic surgery the biological age rather than the chronological age is decisive. In view of the increasingly older population, further studies are urgently needed to optimize patient selection, type of intervention, preoperative planning and postoperative treatment as well as the quality of life. Springer Medizin 2022-11-28 2023 /pmc/articles/PMC9703435/ /pubmed/36441200 http://dx.doi.org/10.1007/s00104-022-01772-y Text en © The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Leitthema Ehrsam, Jonas Peter Aigner, Clemens Chirurgie des alten Menschen – Thoraxchirurgie |
title | Chirurgie des alten Menschen – Thoraxchirurgie |
title_full | Chirurgie des alten Menschen – Thoraxchirurgie |
title_fullStr | Chirurgie des alten Menschen – Thoraxchirurgie |
title_full_unstemmed | Chirurgie des alten Menschen – Thoraxchirurgie |
title_short | Chirurgie des alten Menschen – Thoraxchirurgie |
title_sort | chirurgie des alten menschen – thoraxchirurgie |
topic | Leitthema |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703435/ https://www.ncbi.nlm.nih.gov/pubmed/36441200 http://dx.doi.org/10.1007/s00104-022-01772-y |
work_keys_str_mv | AT ehrsamjonaspeter chirurgiedesaltenmenschenthoraxchirurgie AT aignerclemens chirurgiedesaltenmenschenthoraxchirurgie |