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Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization

Cholesteryl ester (CE)-rich lipid droplets (LDs) accumulate in steroidogenic tissues under physiological conditions and constitute an important source of cholesterol as the precursor for the synthesis of all steroid hormones. The mechanisms specifically involved in CE-rich LD formation have not been...

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Detalles Bibliográficos
Autores principales: Shen, Wen-Jun, Cortez, Yuan, Singh, Amar, Chen, Weiqin, Azhar, Salman, Kraemer, Fredric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703635/
https://www.ncbi.nlm.nih.gov/pubmed/36332685
http://dx.doi.org/10.1016/j.jlr.2022.100309

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