The effect of tacrolimus-induced toxicity on metabolic profiling in target tissues of mice

Tacrolimus (Tac) is a common immunosuppressant that used in organ transplantation. However, its therapeutic index is narrow, and it is prone to adverse side effects, along with an increased risk of toxicity, namely, cardio-, nephro-, hepato-, and neurotoxicity. Prior metabolomic investigations invol...

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Detalles Bibliográficos
Autores principales: Xie, Dadi, Guo, Jinxiu, Dang, Ruili, Li, Yanan, Si, Qingying, Han, Wenxiu, Wang, Shan, Wei, Ning, Meng, Junjun, Wu, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703746/
https://www.ncbi.nlm.nih.gov/pubmed/36443830
http://dx.doi.org/10.1186/s40360-022-00626-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703746/
https://www.ncbi.nlm.nih.gov/pubmed/36443830
http://dx.doi.org/10.1186/s40360-022-00626-x

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