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TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease
BACKGROUND: People with Parkinson’s disease (PD) have a high fall rate and many falls are associated with turns. Despite this, there is minimal research on effects of rehabilitation on the quality of turns. Further, quantifying turns in the home may have broader implications since rehabilitation of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703770/ https://www.ncbi.nlm.nih.gov/pubmed/36443737 http://dx.doi.org/10.1186/s12883-022-02934-5 |
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author | King, LA Carlson-Kuhta, P Wilhelm, JL Lapidus, JA Dale, ML Talman, LS Barlow, N Mancini, M Horak, FB |
author_facet | King, LA Carlson-Kuhta, P Wilhelm, JL Lapidus, JA Dale, ML Talman, LS Barlow, N Mancini, M Horak, FB |
author_sort | King, LA |
collection | PubMed |
description | BACKGROUND: People with Parkinson’s disease (PD) have a high fall rate and many falls are associated with turns. Despite this, there is minimal research on effects of rehabilitation on the quality of turns. Further, quantifying turns in the home may have broader implications since rehabilitation of turns would ideally improve turning in real world mobility. METHODS: Sixty people with PD and a history of falls will be randomized to receive either a novel TURNing InTervention (TURN-IT) or no intervention (control group). The TURN-IT group will be seen for 6 weeks (18 visits) for an individualized, progressive program that is based on the specific constraints of turning in PD. Wearable sensors will be used to measure 7 days of mobility, including turns, before and after intervention or control period. In addition, blinded assessments of gait, mobility and turns will occur before and after intervention for both groups and falls will be monitored for twelve months post intervention with bimonthly email questionnaires. DISCUSSION: This study has the potential to change how we rehabilitate and assess turning in people with PD and falls. There are several novel aspects to our study including a comprehensive turning-focused intervention that is tailored to the underlying constraints that impair turning in people with PD. Further, our outcome measure of turning quality during 7 days of daily life is novel and has implications for determining real-life changes after rehabilitation. The ultimate goal of this rehabilitation intervention is to improve how patients turn in daily life and to reduce falls. TRIALS REGISTRATION: This protocol is registered at clinicaltrials.gov; #NCT04897256; https://clinicaltrials.gov/ct2/show/NCT04897256?term=Horak&cond=Parkinson+Disease&draw=2&rank=4. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12883-022-02934-5. |
format | Online Article Text |
id | pubmed-9703770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-97037702022-11-29 TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease King, LA Carlson-Kuhta, P Wilhelm, JL Lapidus, JA Dale, ML Talman, LS Barlow, N Mancini, M Horak, FB BMC Neurol Study Protocol BACKGROUND: People with Parkinson’s disease (PD) have a high fall rate and many falls are associated with turns. Despite this, there is minimal research on effects of rehabilitation on the quality of turns. Further, quantifying turns in the home may have broader implications since rehabilitation of turns would ideally improve turning in real world mobility. METHODS: Sixty people with PD and a history of falls will be randomized to receive either a novel TURNing InTervention (TURN-IT) or no intervention (control group). The TURN-IT group will be seen for 6 weeks (18 visits) for an individualized, progressive program that is based on the specific constraints of turning in PD. Wearable sensors will be used to measure 7 days of mobility, including turns, before and after intervention or control period. In addition, blinded assessments of gait, mobility and turns will occur before and after intervention for both groups and falls will be monitored for twelve months post intervention with bimonthly email questionnaires. DISCUSSION: This study has the potential to change how we rehabilitate and assess turning in people with PD and falls. There are several novel aspects to our study including a comprehensive turning-focused intervention that is tailored to the underlying constraints that impair turning in people with PD. Further, our outcome measure of turning quality during 7 days of daily life is novel and has implications for determining real-life changes after rehabilitation. The ultimate goal of this rehabilitation intervention is to improve how patients turn in daily life and to reduce falls. TRIALS REGISTRATION: This protocol is registered at clinicaltrials.gov; #NCT04897256; https://clinicaltrials.gov/ct2/show/NCT04897256?term=Horak&cond=Parkinson+Disease&draw=2&rank=4. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12883-022-02934-5. BioMed Central 2022-11-28 /pmc/articles/PMC9703770/ /pubmed/36443737 http://dx.doi.org/10.1186/s12883-022-02934-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Study Protocol King, LA Carlson-Kuhta, P Wilhelm, JL Lapidus, JA Dale, ML Talman, LS Barlow, N Mancini, M Horak, FB TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease |
title | TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease |
title_full | TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease |
title_fullStr | TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease |
title_full_unstemmed | TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease |
title_short | TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson’s disease |
title_sort | turn-it: a novel turning intervention program to improve quality of turning in daily life in people with parkinson’s disease |
topic | Study Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703770/ https://www.ncbi.nlm.nih.gov/pubmed/36443737 http://dx.doi.org/10.1186/s12883-022-02934-5 |
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