Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout

BACKGROUND: Allopurinol (ALP), a xanthine oxidase inhibitor, is a first line drug for the treatment of gout and hyperuricemia. Being the member of BCS class II drugs, ALP has solubility problem, which affects its bioavailability. Also, ALP has shorter half-life and showed GI related problems. In pre...

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Detalles Bibliográficos
Autores principales: Ali, Zakir, Din, Fakhar ud, Zahid, Fatima, Sohail, Saba, Imran, Basalat, Khan, Salman, Malik, Maimoona, Zeb, Alam, Khan, Gul Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703780/
https://www.ncbi.nlm.nih.gov/pubmed/36443818
http://dx.doi.org/10.1186/s40360-022-00625-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703780/
https://www.ncbi.nlm.nih.gov/pubmed/36443818
http://dx.doi.org/10.1186/s40360-022-00625-y

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