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A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity

The spread of COVID-19 to more than 200 countries has shocked the public. Therefore, understanding the dynamics of transmission is very important. In this paper, the COVID-19 mathematical model has been formulated, analyzed, and validated using incident data from West Java Province, Indonesia. The m...

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Autores principales: Anggriani, Nursanti, Ndii, Meksianis Z., Amelia, Rika, Suryaningrat, Wahyu, Pratama, Mochammad Andhika Aji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703878/
http://dx.doi.org/10.1016/j.aej.2021.04.104
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author Anggriani, Nursanti
Ndii, Meksianis Z.
Amelia, Rika
Suryaningrat, Wahyu
Pratama, Mochammad Andhika Aji
author_facet Anggriani, Nursanti
Ndii, Meksianis Z.
Amelia, Rika
Suryaningrat, Wahyu
Pratama, Mochammad Andhika Aji
author_sort Anggriani, Nursanti
collection PubMed
description The spread of COVID-19 to more than 200 countries has shocked the public. Therefore, understanding the dynamics of transmission is very important. In this paper, the COVID-19 mathematical model has been formulated, analyzed, and validated using incident data from West Java Province, Indonesia. The model made considers the asymptomatic and symptomatic compartments and decreased immunity. The model is formulated in the form of a system of differential equations, where the population is divided into seven compartments, namely Susceptible Population [Formula: see text] , Exposed Population [Formula: see text] , Asymptomatic Infection Population [Formula: see text] , Symptomatic Infection Population [Formula: see text] , Recovered Population [Formula: see text] , Susceptible Populations previously infected [Formula: see text] , and Quarantine population [Formula: see text]. The results show that there has been an outbreak of COVID-19 in West Java Province, Indonesia. This can be seen from the basic reproduction number of this model, which is 3.180126127 [Formula: see text]. Also, the numerical simulation results show that waning immunity can increase the occurrence of outbreaks; and a period of isolation can slow down the process of spreading COVID-19. So if a strict social distancing policy is enforced like a quarantine, the outbreak will lessen.
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spelling pubmed-97038782022-11-28 A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity Anggriani, Nursanti Ndii, Meksianis Z. Amelia, Rika Suryaningrat, Wahyu Pratama, Mochammad Andhika Aji Alexandria Engineering Journal Article The spread of COVID-19 to more than 200 countries has shocked the public. Therefore, understanding the dynamics of transmission is very important. In this paper, the COVID-19 mathematical model has been formulated, analyzed, and validated using incident data from West Java Province, Indonesia. The model made considers the asymptomatic and symptomatic compartments and decreased immunity. The model is formulated in the form of a system of differential equations, where the population is divided into seven compartments, namely Susceptible Population [Formula: see text] , Exposed Population [Formula: see text] , Asymptomatic Infection Population [Formula: see text] , Symptomatic Infection Population [Formula: see text] , Recovered Population [Formula: see text] , Susceptible Populations previously infected [Formula: see text] , and Quarantine population [Formula: see text]. The results show that there has been an outbreak of COVID-19 in West Java Province, Indonesia. This can be seen from the basic reproduction number of this model, which is 3.180126127 [Formula: see text]. Also, the numerical simulation results show that waning immunity can increase the occurrence of outbreaks; and a period of isolation can slow down the process of spreading COVID-19. So if a strict social distancing policy is enforced like a quarantine, the outbreak will lessen. THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. 2022-01 2021-05-14 /pmc/articles/PMC9703878/ http://dx.doi.org/10.1016/j.aej.2021.04.104 Text en © 2021 THE AUTHORS Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Anggriani, Nursanti
Ndii, Meksianis Z.
Amelia, Rika
Suryaningrat, Wahyu
Pratama, Mochammad Andhika Aji
A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity
title A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity
title_full A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity
title_fullStr A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity
title_full_unstemmed A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity
title_short A mathematical COVID-19 model considering asymptomatic and symptomatic classes with waning immunity
title_sort mathematical covid-19 model considering asymptomatic and symptomatic classes with waning immunity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703878/
http://dx.doi.org/10.1016/j.aej.2021.04.104
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