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Stroke-related length of hospitalization trends and in-hospital mortality in Peru

BACKGROUND: Peru faces challenges to provide adequate care to stroke patients. Length of hospitalization and in-hospital mortality are two well-known indicators of stroke care. We aimed to describe the length of stay (LOS) of stroke in Peru, and to assess in-hospital mortality risk due to stroke, an...

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Autores principales: Labán-Seminario, L. Max, Carrillo-Larco, Rodrigo M., Bernabé-Ortiz, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703986/
https://www.ncbi.nlm.nih.gov/pubmed/36452071
http://dx.doi.org/10.7717/peerj.14467
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author Labán-Seminario, L. Max
Carrillo-Larco, Rodrigo M.
Bernabé-Ortiz, Antonio
author_facet Labán-Seminario, L. Max
Carrillo-Larco, Rodrigo M.
Bernabé-Ortiz, Antonio
author_sort Labán-Seminario, L. Max
collection PubMed
description BACKGROUND: Peru faces challenges to provide adequate care to stroke patients. Length of hospitalization and in-hospital mortality are two well-known indicators of stroke care. We aimed to describe the length of stay (LOS) of stroke in Peru, and to assess in-hospital mortality risk due to stroke, and subtypes. METHODS: This retrospective cohort study used hospitalization registries coding with ICD-10 from 2002 to 2017 (N = 98,605) provided by the Ministry of Health; in-hospital mortality was available for 2016–2017 (N = 6,566). Stroke cases aged ≥35 years were divided into subarachnoid hemorrhage (I60), intracerebral hemorrhage (I61), cerebral infarction (I63), and stroke not specified as hemorrhage or infarction (I64). Data included stroke LOS and in-hospital mortality; socio-demographic and clinical variables. We fitted a region- and hospital level-stratified Weibull proportional hazard model to assess the in-hospital mortality. RESULTS: The median LOS was 7 days (IQR: 4–13). Hemorrhagic strokes had median LOS longer than ischemic strokes and stroke not specified as hemorrhage or infarction (P = <0.001). The case fatality rate (CFR) of patients with stroke was 11.5% (95% CI [10–12%]). Subarachnoid hemorrhage (HR = 2.45; 95% CI [1.91–3.14]), intracerebral hemorrhage (HR = 1.95; 95% CI [1.55–2.46]), and stroke not specified as hemorrhage or infarction (HR = 1.45; 95% CI [1.16–1.81]) were associated with higher in-hospital mortality risk in comparison to ischemic strokes. DISCUSSION: Between 2002 and 2017, LOS due to stroke has not changed in Peru in stroke patients discharged alive. Hemorrhagic cases had the longest LOS and highest in-hospital mortality risk during 2016 and 2017. The findings of our study seem to be consistent with a previous study carried out in Peru and similar to that of HIC and LMIC, also there is an increased median LOS in stroke cases managed in specialized centers. Likewise, LOS seems to depend on the type of stroke, where ischemic stroke cases have the lowest LOS. Peru needs to improve access to stroke care.
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spelling pubmed-97039862022-11-29 Stroke-related length of hospitalization trends and in-hospital mortality in Peru Labán-Seminario, L. Max Carrillo-Larco, Rodrigo M. Bernabé-Ortiz, Antonio PeerJ Epidemiology BACKGROUND: Peru faces challenges to provide adequate care to stroke patients. Length of hospitalization and in-hospital mortality are two well-known indicators of stroke care. We aimed to describe the length of stay (LOS) of stroke in Peru, and to assess in-hospital mortality risk due to stroke, and subtypes. METHODS: This retrospective cohort study used hospitalization registries coding with ICD-10 from 2002 to 2017 (N = 98,605) provided by the Ministry of Health; in-hospital mortality was available for 2016–2017 (N = 6,566). Stroke cases aged ≥35 years were divided into subarachnoid hemorrhage (I60), intracerebral hemorrhage (I61), cerebral infarction (I63), and stroke not specified as hemorrhage or infarction (I64). Data included stroke LOS and in-hospital mortality; socio-demographic and clinical variables. We fitted a region- and hospital level-stratified Weibull proportional hazard model to assess the in-hospital mortality. RESULTS: The median LOS was 7 days (IQR: 4–13). Hemorrhagic strokes had median LOS longer than ischemic strokes and stroke not specified as hemorrhage or infarction (P = <0.001). The case fatality rate (CFR) of patients with stroke was 11.5% (95% CI [10–12%]). Subarachnoid hemorrhage (HR = 2.45; 95% CI [1.91–3.14]), intracerebral hemorrhage (HR = 1.95; 95% CI [1.55–2.46]), and stroke not specified as hemorrhage or infarction (HR = 1.45; 95% CI [1.16–1.81]) were associated with higher in-hospital mortality risk in comparison to ischemic strokes. DISCUSSION: Between 2002 and 2017, LOS due to stroke has not changed in Peru in stroke patients discharged alive. Hemorrhagic cases had the longest LOS and highest in-hospital mortality risk during 2016 and 2017. The findings of our study seem to be consistent with a previous study carried out in Peru and similar to that of HIC and LMIC, also there is an increased median LOS in stroke cases managed in specialized centers. Likewise, LOS seems to depend on the type of stroke, where ischemic stroke cases have the lowest LOS. Peru needs to improve access to stroke care. PeerJ Inc. 2022-11-25 /pmc/articles/PMC9703986/ /pubmed/36452071 http://dx.doi.org/10.7717/peerj.14467 Text en © 2022 Labán-Seminario et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Epidemiology
Labán-Seminario, L. Max
Carrillo-Larco, Rodrigo M.
Bernabé-Ortiz, Antonio
Stroke-related length of hospitalization trends and in-hospital mortality in Peru
title Stroke-related length of hospitalization trends and in-hospital mortality in Peru
title_full Stroke-related length of hospitalization trends and in-hospital mortality in Peru
title_fullStr Stroke-related length of hospitalization trends and in-hospital mortality in Peru
title_full_unstemmed Stroke-related length of hospitalization trends and in-hospital mortality in Peru
title_short Stroke-related length of hospitalization trends and in-hospital mortality in Peru
title_sort stroke-related length of hospitalization trends and in-hospital mortality in peru
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703986/
https://www.ncbi.nlm.nih.gov/pubmed/36452071
http://dx.doi.org/10.7717/peerj.14467
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