Cargando…

The Immunomodulatory Functions of BTK Inhibition in the Central Nervous System

Bruton’s tyrosine kinase (BTK) is a central signaling node in B cells. BTK inhibition has witnessed great success in the treatment of B-cell malignancies. Additionally, in the immune system, BTK is also a prominent component linking a wide variety of immune-related pathways. Therefore, more and more...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Tingyu, Wang, Zengguang, Zhu, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704002/ https://www.ncbi.nlm.nih.gov/pubmed/36452053 http://dx.doi.org/10.2147/JIR.S389958

Ejemplares similares

Genomic Profiling Reveals Differences in Primary Central Nervous System Lymphoma and Large B-Cell Lymphoma, With Subtyping Suggesting Sensitivity to BTK Inhibition
por: Severson, Eric A, et al.
Publicado: (2023)

Sustained response following BTK inhibitors based treatment in HIV-related primary central nervous system lymphoma: case report
por: Zhou, Ying, et al.
Publicado: (2023)

Revealing Pan-Histology Immunomodulatory Targets in Pediatric Central Nervous System Tumors
por: Galvin, Robert T., et al.
Publicado: (2023)

Multifaceted Immunomodulatory Effects of the BTK Inhibitors Ibrutinib and Acalabrutinib on Different Immune Cell Subsets – Beyond B Lymphocytes
por: Zhu, Sining, et al.
Publicado: (2021)

The Form and Functions of the Central Nervous System
Publicado: (1921)

Functional bioengineered models of the central nervous system
por: Rouleau, Nicolas, et al.
Publicado: (2023)

BTK inhibitor combined with anti-PD-1 monoclonal antibody for the treatment of CD20-negative primary central nervous system lymphoma: A case report
por: Feng, Lan, et al.
Publicado: (2022)

Case report: CD19-directed CAR-T cell therapy combined with BTK inhibitor and PD-1 antibody against secondary central nervous system lymphoma
por: Zhang, Wenqi, et al.
Publicado: (2022)

Central nervous system myelin: structure, function, and pathology
por: Deber, Charles M., et al.
Publicado: (1991)

Modulation of lymphatic transport in the central nervous system
por: Li, Wenzhong, et al.
Publicado: (2022)

Reining in BTK: Interdomain Interactions and Their Importance in the Regulatory Control of BTK
por: Kueffer, Lauren E., et al.
Publicado: (2021)

Acquired BTK mutations associated with resistance to noncovalent BTK inhibitors
por: Qi, Jialei, et al.
Publicado: (2023)

The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View
por: Tambaro, Francesco Paolo, et al.
Publicado: (2021)

Vascularisation of the central nervous system
por: Tata, Mathew, et al.
Publicado: (2015)

Mucormycosis of the Central Nervous System
por: Chikley, Amanda, et al.
Publicado: (2019)

Synaptic inhibition and γ-aminobutyric acid in the mammalian central nervous system
por: OBATA, Kunihiko
Publicado: (2013)

Zinc and Central Nervous System Disorders
por: Wang, Bangqi, et al.
Publicado: (2023)

The Form and Functions of the Central Nervous System, Second Edition
Publicado: (1924)

Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
por: Zou, Shenglong, et al.
Publicado: (2018)

Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI
por: Nicolson, Phillip L.R., et al.
Publicado: (2018)

Managing Waldenström’s macroglobulinemia with BTK inhibitors
por: Buske, Christian, et al.
Publicado: (2022)

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function
por: Trory, Justin S., et al.
Publicado: (2022)

The emerging roles of ferroptosis in cells of the central nervous system
por: Li, Yuyao, et al.
Publicado: (2022)

The Central Nervous System of Vertebrates
por: Nicholls, J. G.
Publicado: (1967)

The Central Nervous System and Behavior
por: May, Mark A.
Publicado: (1959)

Structure of the Central Nervous System
Publicado: (1891)

Coronaviruses and the central nervous system
por: Morgello, Susan
Publicado: (2020)

Integrin Signaling Shaping BTK-Inhibitor Resistance
por: Polcik, Laura, et al.
Publicado: (2022)

Ibrutinib and novel BTK inhibitors in clinical development
por: Akinleye, Akintunde, et al.
Publicado: (2013)

Effects of BTK signalling in pathogenic microorganism infections
por: Ye, Bingjue, et al.
Publicado: (2019)

Current and novel BTK inhibitors in Waldenström’s macroglobulinemia
por: Ntanasis-Stathopoulos, Ioannis, et al.
Publicado: (2021)

The role of the Rho/ROCK signaling pathway in inhibiting axonal regeneration in the central nervous system
por: Liu, Jing, et al.
Publicado: (2015)

Rare central nervous system lymphomas
por: Kaji, Furqaan Ahmed, et al.
Publicado: (2022)

Cytokines and Myelination in the Central Nervous System
por: Schmitz, Thomas, et al.
Publicado: (2008)

Imaging the fetal central nervous system
por: De Keersmaecker, B., et al.
Publicado: (2011)

Histopathology of the Peripheral and Central Nervous System
Publicado: (1934)

Primary central nervous system lymphoma
por: Löw, Sarah, et al.
Publicado: (2018)

Rickettsial infections of the central nervous system
por: Sekeyová, Zuzana, et al.
Publicado: (2019)

Glycosaminoglycans and Glycomimetics in the Central Nervous System
por: Rowlands, Dáire, et al.
Publicado: (2015)

Is Ghrelin Synthesized in the Central Nervous System?
por: Cabral, Agustina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5skk8t2nb74m2d75qatts38nu5