Novel Mucoadhesive Chitosomes as a Platform for Enhanced Oral Bioavailability of Cinnarizine

PURPOSE: Cinnarizine (CIN) is a class II BSC drug, suffering from erratic bioavailability due to its pH-dependent solubility. It has preferential absorption in the stomach. In this study, new chitosan (CS) coated niosomes of CIN (CIN-loaded chitosomes) have been developed to extend the gastric reten...

Descripción completa

Detalles Bibliográficos
Autores principales: Oransa, Hagar Ahmed, Boughdady, Mariza Fouad, EL-Sabbagh, Hassan Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704018/
https://www.ncbi.nlm.nih.gov/pubmed/36452306
http://dx.doi.org/10.2147/IJN.S384494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704018/
https://www.ncbi.nlm.nih.gov/pubmed/36452306
http://dx.doi.org/10.2147/IJN.S384494

Ejemplares similares