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Solid lipid nanoparticle as an effective drug delivery system of a novel curcumin derivative: formulation, release in vitro and pharmacokinetics in vivo
CONTEXT: Curcumin (Cur) has a short duration of action which limits its therapeutic efficacy. Carbonic acid 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 4-[7-(4-hydroxy-3-methoxy-phenyl)-3,5-dioxo-hepta-1,6-dienyl]-2...
Autores principales: | Zhao, Wenmei, Zeng, Mingtang, Li, Ke, Pi, Chao, Liu, Zerong, Zhan, Chenglin, Yuan, Jiyuan, Su, Zhilian, Wei, Yuxun, Wen, Jie, Pi, Fengjuan, Song, Xinjie, Lee, Robert J., Wei, Yumeng, Zhao, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704087/ https://www.ncbi.nlm.nih.gov/pubmed/36606719 http://dx.doi.org/10.1080/13880209.2022.2136205 |
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