NUMB as a Therapeutic Target for Melanoma

The upregulation of the adaptor protein NUMB triggers melanocytic differentiation from multipotent skin stem cells, which share many properties with aggressive melanoma cells. Although NUMB acts as a tumor suppressor in various human cancer types, little is known about its role in melanoma. In this...

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Detalles Bibliográficos
Autores principales: Hristova, Denitsa M., Fukumoto, Takeshi, Takemori, Chihiro, Gao, Le, Hua, Xia, Wang, Joshua X., Li, Ling, Beqiri, Marilda, Watters, Andrea, Vultur, Adina, Gimie, Yusra, Rebecca, Vito, Samarkina, Anastasia, Jimbo, Haruki, Nishigori, Chikako, Zhang, Jie, Cheng, Chaoran, Wei, Zhi, Somasundaram, Rajasekharan, Fukunaga-Kalabis, Mizuho, Herlyn, Meenhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704357/
https://www.ncbi.nlm.nih.gov/pubmed/34883044
http://dx.doi.org/10.1016/j.jid.2021.11.027

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