Cargando…

Apurinic/apyrimidinic endonuclease triggered doxorubicin-releasing DNA nanoprism for target therapy

Drug delivery and triggered release in tumor cells would realize the ultimate goal of precise cancer treatment. An APE1 triggered DNA nanoprism was designed, aiming at the applications of both drug delivery and precise triggered drug release in cancer cell. We demonstrate that the AP-Prism was succe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Meng, Li, Na, Liu, Fei, Zeng, Nan, Yu, Changyuan, Li, Shuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704400/ https://www.ncbi.nlm.nih.gov/pubmed/35943146 http://dx.doi.org/10.1080/15384101.2022.2108567

Ejemplares similares

Apurinic/Apyrimidinic Endonuclease 1 and Tyrosyl-DNA Phosphodiesterase 1 Prevent Suicidal Covalent DNA-Protein Crosslink at Apurinic/Apyrimidinic Site
por: Lebedeva, Natalia A., et al.
Publicado: (2021)

Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma
por: Xie, Jiayin, et al.
Publicado: (2014)

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1
por: Simeonov, Anton, et al.
Publicado: (2009)

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori
por: Turgimbayeva, Aigerim, et al.
Publicado: (2018)

Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
por: Schein, Catherine H, et al.
Publicado: (2002)

Apurinic/apyrimidinic endonuclease 1 is a key modulator of aluminum-induced neuroinflammation
por: Zaky, Amira, et al.
Publicado: (2013)

Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor
por: Manvilla, Brittney A., et al.
Publicado: (2013)

Endonuclease IV Is the Major Apurinic/Apyrimidinic Endonuclease in Mycobacterium tuberculosis and Is Important for Protection against Oxidative Damage
por: Puri, Rupangi Verma, et al.
Publicado: (2013)

Altered Endoribonuclease Activity of Apurinic/Apyrimidinic Endonuclease 1 Variants Identified in the Human Population
por: Kim, Wan Cheol, et al.
Publicado: (2014)

A specific DNA-nanoprobe for tracking the activities of human apurinic/apyrimidinic endonuclease 1 in living cells
por: Zhai, Junqiu, et al.
Publicado: (2017)

Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L
por: Joldybayeva, Botagoz, et al.
Publicado: (2014)

Association of Leukotrichia in Vitiligo and Asp148Glu Polymorphism of Apurinic/Apyrimidinic Endonuclease 1
por: Aydin, A. Fatih, et al.
Publicado: (2017)

Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases
por: Kuznetsova, Alexandra A., et al.
Publicado: (2021)

Human and bacterial TatD enzymes exhibit apurinic/apyrimidinic (AP) endonuclease activity
por: Dorival, Jonathan, et al.
Publicado: (2023)

Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites
por: Minko, Irina G., et al.
Publicado: (2016)

Apurinic/Apyrimidinic Endonucleases of Mycobacterium tuberculosis Protect against DNA Damage but Are Dispensable for the Growth of the Pathogen in Guinea Pigs
por: Puri, Rupangi Verma, et al.
Publicado: (2014)

Visualizing the coordination of apurinic/apyrimidinic endonuclease (APE1) and DNA polymerase β during base excision repair
por: Fairlamb, Max S., et al.
Publicado: (2023)

Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)
por: Jackson, Elias B., et al.
Publicado: (2005)

Prognostic Value of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) Expression in Breast Cancer
por: Woo, Joohyun, et al.
Publicado: (2014)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L
Publicado: (2014)

Elevation of the Serum Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 in Coronary Artery Disease
por: Jin, Seon-Ah, et al.
Publicado: (2015)

Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway
por: Kuznetsova, Alexandra A, et al.
Publicado: (2018)

Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA
por: Wang, Wei-Wei, et al.
Publicado: (2018)

miR-513a-5p regulates radiosensitivity of osteosarcoma by targeting human apurinic/apyrimidinic endonuclease
por: Dai, Nan, et al.
Publicado: (2016)

Activity of Human Apurinic/Apyrimidinic Endonuclease APE1 Toward Damaged DNA and Native RNA With Non-canonical Structures
por: Davletgildeeva, Anastasia T., et al.
Publicado: (2020)

Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-dependent manner in human osteosarcoma
por: Jiang, Xuan, et al.
Publicado: (2015)

Human Apurinic/Apyrimidinic Endonuclease siRNA Inhibits the Angiogenesis Induced by X-Ray Irradiation in Lung Cancer Cells
por: Gu, Xianqing, et al.
Publicado: (2013)

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA
por: Barnes, Tavish, et al.
Publicado: (2009)

Identification of a residue critical for the excision of 3′-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family
por: Castillo-Acosta, Víctor M., et al.
Publicado: (2009)

Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus
por: Kiyonari, Shinichi, et al.
Publicado: (2009)

High-Resolution Crystal Structures Reveal Plasticity in the Metal Binding Site of Apurinic/Apyrimidinic Endonuclease I
por: He, Hongzhen, et al.
Publicado: (2014)

The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1
por: Bulygin, Anatoly A., et al.
Publicado: (2020)

Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity
por: Roychoudhury, Shrabasti, et al.
Publicado: (2017)

The antioxidant and DNA-repair enzyme apurinic/apyrimidinic endonuclease 1 limits the development of tubulointerstitial fibrosis partly by modulating the immune system
por: Maruyama, Keisuke, et al.
Publicado: (2019)

DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling
por: Krumkacheva, Olesya A, et al.
Publicado: (2019)

The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes
por: Baek, Hyunjung, et al.
Publicado: (2016)

Elevated Plasma Apurinic/Apyrimidinic Endonuclease 1/Redox Effector Factor-1 Levels in Refractory Kawasaki Disease
por: Lee, Yu-Ran, et al.
Publicado: (2022)

Kinetic Features of 3′–5′–Exonuclease Activity of Apurinic/Apyrimidinic Endonuclease Apn2 from Saccharomyces cerevisiae
por: Kuznetsova, Aleksandra A., et al.
Publicado: (2022)

Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites
por: Lebedeva, Natalia A., et al.
Publicado: (2012)

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1
por: Sui, Jiangdong, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_so3jjb8n8go89mott2gofv751u