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The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors

Type III CRISPR–Cas systems make use of a multi-subunit effector complex to target foreign (m)RNA transcripts complementary to the guide/CRISPR RNA (crRNA). Base-pairing of the target RNA with specialized regions in the crRNA not only triggers target RNA cleavage, but also activates the characterist...

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Detalles Bibliográficos
Autores principales: Steens, Jurre A., Salazar, Carl Raymund P., Staals, Raymond H.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704534/
https://www.ncbi.nlm.nih.gov/pubmed/36282000
http://dx.doi.org/10.1042/BST20220289