Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains

Cerebral organoids show great promise as tools to unravel the complex mechanisms by which the mammalian brain develops during embryogenesis. We generated mouse cerebral organoids harbouring constitutive or conditional mutations in Pax6, which encodes a transcription factor with multiple important ro...

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Detalles Bibliográficos
Autores principales: Ferdaos, Nurfarhana, Lowell, Sally, Mason, John O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704552/
https://www.ncbi.nlm.nih.gov/pubmed/36441708
http://dx.doi.org/10.1371/journal.pone.0278147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704552/
https://www.ncbi.nlm.nih.gov/pubmed/36441708
http://dx.doi.org/10.1371/journal.pone.0278147

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