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Cas9-mediated endogenous plasmid loss in Borrelia burgdorferi

The spirochete Borrelia burgdorferi, which causes Lyme disease, has the most segmented genome among known bacteria. In addition to a linear chromosome, the B. burgdorferi genome contains over 20 linear and circular endogenous plasmids. While many of these plasmids are dispensable under in vitro cult...

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Detalles Bibliográficos
Autores principales: Takacs, Constantin N., Nakajima, Yuko, Haber, James E., Jacobs-Wagner, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704580/
https://www.ncbi.nlm.nih.gov/pubmed/36441794
http://dx.doi.org/10.1371/journal.pone.0278151