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Risk factors and survival in patients with COVID-19 in northeastern Brazil

BACKGROUND: Knowledge about the epidemiology and risk factors surrounding COVID-19 contributes to developing better health strategies to combat the disease. OBJECTIVE: This study aimed to establish a survival analysis and identify the risk factors for patients with COVID-19 in an upper middle-income...

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Autores principales: Fernandes, Ana Tereza, Rodrigues, Eujessika K., Araújo, Eder R., Formiga, Magno F., Horan, Priscilla K. Sá, Ferreira, Ana Beatriz Nunes de Sousa, Barbosa, Humberto A., Barbosa, Paulo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704671/
https://www.ncbi.nlm.nih.gov/pubmed/36441799
http://dx.doi.org/10.1371/journal.pone.0278213
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author Fernandes, Ana Tereza
Rodrigues, Eujessika K.
Araújo, Eder R.
Formiga, Magno F.
Horan, Priscilla K. Sá
Ferreira, Ana Beatriz Nunes de Sousa
Barbosa, Humberto A.
Barbosa, Paulo S.
author_facet Fernandes, Ana Tereza
Rodrigues, Eujessika K.
Araújo, Eder R.
Formiga, Magno F.
Horan, Priscilla K. Sá
Ferreira, Ana Beatriz Nunes de Sousa
Barbosa, Humberto A.
Barbosa, Paulo S.
author_sort Fernandes, Ana Tereza
collection PubMed
description BACKGROUND: Knowledge about the epidemiology and risk factors surrounding COVID-19 contributes to developing better health strategies to combat the disease. OBJECTIVE: This study aimed to establish a survival analysis and identify the risk factors for patients with COVID-19 in an upper middle-income city in Brazil. METHODS: A retrospective cohort study was conducted with 280 hospitalized patients with COVID-19. The eCOVID platform provided data to monitor COVID-19 cases and help the communication between professionals. RESULTS: Age ≥ 65 years was associated with decreased survival (54.8%), and females had a lower survival rate than males (p = 0.01). Regarding risk factors, urea concentration (p<0.001), hospital length of stay (p = 0.002), oxygen concentration (p = 0.005), and age (p = 0.02) were associated with death. CONCLUSION: Age, hospital length of stay, high blood urea concentration, and low oxygen concentration were associated with death by COVID-19 in the studied population. These findings corroborate with studies conducted in research centers worldwide.
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spelling pubmed-97046712022-11-29 Risk factors and survival in patients with COVID-19 in northeastern Brazil Fernandes, Ana Tereza Rodrigues, Eujessika K. Araújo, Eder R. Formiga, Magno F. Horan, Priscilla K. Sá Ferreira, Ana Beatriz Nunes de Sousa Barbosa, Humberto A. Barbosa, Paulo S. PLoS One Research Article BACKGROUND: Knowledge about the epidemiology and risk factors surrounding COVID-19 contributes to developing better health strategies to combat the disease. OBJECTIVE: This study aimed to establish a survival analysis and identify the risk factors for patients with COVID-19 in an upper middle-income city in Brazil. METHODS: A retrospective cohort study was conducted with 280 hospitalized patients with COVID-19. The eCOVID platform provided data to monitor COVID-19 cases and help the communication between professionals. RESULTS: Age ≥ 65 years was associated with decreased survival (54.8%), and females had a lower survival rate than males (p = 0.01). Regarding risk factors, urea concentration (p<0.001), hospital length of stay (p = 0.002), oxygen concentration (p = 0.005), and age (p = 0.02) were associated with death. CONCLUSION: Age, hospital length of stay, high blood urea concentration, and low oxygen concentration were associated with death by COVID-19 in the studied population. These findings corroborate with studies conducted in research centers worldwide. Public Library of Science 2022-11-28 /pmc/articles/PMC9704671/ /pubmed/36441799 http://dx.doi.org/10.1371/journal.pone.0278213 Text en © 2022 Fernandes et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fernandes, Ana Tereza
Rodrigues, Eujessika K.
Araújo, Eder R.
Formiga, Magno F.
Horan, Priscilla K. Sá
Ferreira, Ana Beatriz Nunes de Sousa
Barbosa, Humberto A.
Barbosa, Paulo S.
Risk factors and survival in patients with COVID-19 in northeastern Brazil
title Risk factors and survival in patients with COVID-19 in northeastern Brazil
title_full Risk factors and survival in patients with COVID-19 in northeastern Brazil
title_fullStr Risk factors and survival in patients with COVID-19 in northeastern Brazil
title_full_unstemmed Risk factors and survival in patients with COVID-19 in northeastern Brazil
title_short Risk factors and survival in patients with COVID-19 in northeastern Brazil
title_sort risk factors and survival in patients with covid-19 in northeastern brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704671/
https://www.ncbi.nlm.nih.gov/pubmed/36441799
http://dx.doi.org/10.1371/journal.pone.0278213
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