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Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation

Uterine leiomyoma is the most common tumor in women and causes severe morbidity in 15 to 30% of reproductive-age women. Epidemiological studies consistently indicate a correlation between leiomyoma development and exposure to endocrine-disrupting chemical phthalates, especially di-(2-ethylhexyl) pht...

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Detalles Bibliográficos
Autores principales: Iizuka, Takashi, Yin, Ping, Zuberi, Azna, Kujawa, Stacy, Coon, John S., Björvang, Richelle D., Damdimopoulou, Pauliina, Pacyga, Diana C., Strakovsky, Rita S., Flaws, Jodi A., Bulun, Serdar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704719/
https://www.ncbi.nlm.nih.gov/pubmed/36375056
http://dx.doi.org/10.1073/pnas.2208886119